Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 3/20 | 0.54 |
| ▸ | MMP3 | P08254 | 3/20 | 0.53 |
| ▸ | MMP1 | P03956 | 1/20 | 0.53 |
| ▸ | MMP9 | P14780 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | ATM | Q13315 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | CTSK | P43235 | 3/20 | 0.49 |
| ▸ | CTSS | P25774 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23584074 | 1.00 | REN (0.54) | RENMMP3MMP1MMP9POLB | |
| SCHEMBL24356018 | 0.88 | BIRC2 (0.58) | MMP3MMP1ALDH1A1MMP2 | |
| SCHEMBL22110562 | 0.86 | REN (0.54) | RENMMP3MMP1CTSKMMP2 | |
| SCHEMBL28999982 | 0.84 | REN (0.53) | RENMMP3MMP1MMP9POLB | |
| SCHEMBL17015153 | 0.82 | POLB (0.59) | RENPOLBMAPTNPSR1ATM | |
| SCHEMBL15223640 | 0.82 | POLB (0.59) | RENPOLBMAPTNPSR1ATM | |
| SCHEMBL28585446 | 0.82 | REN (0.47) | RENMMP3MMP1MMP9POLB | |
| SCHEMBL6294957 | 0.82 | MMP3 (0.49) | RENMMP3MMP1MMP9POLB | |
| SCHEMBL22130539 | 0.82 | ERAP2 (0.62) | MMP3MMP1MMP2 | |
| SCHEMBL25533190 | 0.81 | POLB (0.56) | RENPOLBMAPTNPSR1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230159593-A1 | CYCLOSPORINE ANALOGUES | UCL BUSINESS LTD (GB) | 2023-05-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230159593-A1 | CYCLOSPORINE ANALOGUES | HAVCR2, CHP1, HLA-C | REN 2907/4885MMP3 1897/4885MMP1 2974/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.