Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 2/20 | 0.53 |
| ▸ | CTSS | P25774 | 1/20 | 0.50 |
| ▸ | CTSK | P43235 | 1/20 | 0.50 |
| ▸ | MMP1 | P03956 | 2/20 | 0.48 |
| ▸ | MMP2 | P08253 | 1/20 | 0.48 |
| ▸ | MMP12 | P39900 | 1/20 | 0.48 |
| ▸ | MMP13 | P45452 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | MMP3 | P08254 | 1/20 | 0.46 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.46 |
| ▸ | CYP3A7 | P24462 | 1/20 | 0.46 |
| ▸ | CYP3A43 | Q9HB55 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28999980 | 0.94 | REN (0.55) | RENCTSSCTSKMMP1POLB | |
| SCHEMBL28599750 | 0.88 | CTSK (0.53) | RENCTSSCTSKMMP1POLB | |
| SCHEMBL23584074 | 0.84 | REN (0.54) | RENCTSSCTSKMMP1MMP2 | |
| SCHEMBL25533404 | 0.84 | REN (0.54) | RENCTSSCTSKMMP1MMP2 | |
| SCHEMBL84540 | 0.83 | BIRC2 (0.54) | RENCYP3A4CYP3A5CYP3A7CYP3A43 | |
| SCHEMBL13893311 | 0.83 | BIRC2 (0.54) | RENCYP3A4CYP3A5CYP3A7CYP3A43 | |
| SCHEMBL19474595 | 0.83 | BIRC2 (0.54) | RENCYP3A4CYP3A5CYP3A7CYP3A43 | |
| SCHEMBL17452195 | 0.83 | CTSS (0.63) | RENCTSSCTSKCTSLCTSB | |
| SCHEMBL29196408 | 0.83 | CAPN1 (0.46) | RENCTSSCTSKMMP1POLB | |
| SCHEMBL29196412 | 0.83 | CAPN1 (0.46) | RENCTSSCTSKMMP1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113024637-B | Method for preparing carfilzomib by taking water-soluble alkynylamide as condensing agent | 江西师范大学 | 2023-05-16 | — | — | CN | disclosed |