Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 6/20 | 0.84 |
| ▸ | PPARG | P37231 | 4/20 | 0.84 |
| ▸ | AGTR2 | P50052 | 4/20 | 0.84 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.84 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.84 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.84 |
| ▸ | USP2 | O75604 | 1/20 | 0.84 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.84 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.84 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.84 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.84 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.84 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.84 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.84 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.84 |
| ▸ | ACE | P12821 | 1/20 | 0.84 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.84 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.84 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.84 |
| ▸ | PDE4A | P27815 | 1/20 | 0.84 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3229877 | 0.94 | PPARG (0.84) | AGTR1PPARGAGTR2KDM4EABCC3 | |
| SCHEMBL12606482 | 0.94 | AGTR1 (0.73) | AGTR1PPARGAGTR2KDM4EABCC3 | |
| SCHEMBL17948609 | 0.93 | PPARG (0.84) | AGTR1PPARGAGTR2KDM4EABCC3 | |
| SCHEMBL19432748 | 0.92 | PPARG (0.81) | AGTR1PPARGAGTR2KDM4EABCC3 | |
| SCHEMBL10021554 | 0.92 | AGTR1 (0.80) | AGTR1PPARGAGTR2KDM4EABCC3 | |
| SCHEMBL170874 | 0.92 | PPARG (0.80) | AGTR1PPARGAGTR2KDM4EABCC3 | |
| SCHEMBL6080037 | 0.92 | AGTR1 (0.75) | AGTR1PPARGAGTR2KDM4EABCC3 | |
| SCHEMBL9229548 | 0.91 | AGTR1 (0.85) | AGTR1PPARGAGTR2KDM4EABCC3 | |
| Telmisartan SCHEMBL4464 | 0.91 | AGTR1 (1.00) | AGTR1PPARGAGTR2KDM4EABCC3 | |
| SCHEMBL17946015 | 0.91 | PPARG (0.88) | AGTR1PPARGAGTR2KDM4EABCC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060211866-A1 | Process for the preparation of angiotensin receptor blockers and intermediates thereof | GLENMARK PHARMACEUTICALS LIMITED (IN) | 2006-09-21 | — | — | US | claimed |
| US-8293777-B2 | Angiotensin II receptor antagonists | MERCK SHARP & DOHME, CORP. (US) | 2012-10-23 | — | — | US | disclosed |
| US-8252825-B2 | Angiotensin II receptor antagonists | NICOX (IT) | 2012-08-28 | — | — | US | disclosed |
| WO-2012028925-A2 | AN IMPROVED PROCESS FOR THE PREPARATION OF TELMISARTAN | OGENE SYSTEMS (I) PVT LTD (IN) | 2012-03-08 | — | — | WO | disclosed |
| US-8106034-B2 | Angiotensin II receptor antagonists | MERCK SHARP & DOHME CORP. (US) | 2012-01-31 | — | — | US | disclosed |
| US-8053455-B2 | Angiotensin II receptor antagonists | MERCK SHARP & DOHME CORP. (US) | 2011-11-08 | — | — | US | disclosed |
| WO-2011102645-A2 | AN IMPROVED PROCESS FOR PREPARING TELMISARTAN | DONG WHA PHARM. CO., LTD. (KR) | 2011-08-25 | — | — | WO | disclosed |
| US-20110201621-A1 | ANGIOTENSIN II RECEPTOR ANTAGONISTS | MERCK SHARP & DOHME CORP. (US) | 2011-08-18 | — | — | US | disclosed |
| US-7947664-B2 | Angiotensin II receptor antagonists | MERCK SHARP & DOHME CORP. (US) | 2011-05-24 | — | — | US | disclosed |
| US-7943781-B2 | Process for preparing telmisartan | DR. REDDY'S LABORATORIES LIMITED (IN) | 2011-05-17 | — | — | US | disclosed |
| US-20100144810-A1 | ANGIOTENSIN II RECEPTOR ANTAGONISTS | MERCK SHARP & DOHME CORP. | 2010-06-10 | — | — | US | disclosed |
| WO-2009006860-A2 | A METHOD OF MANUFACTURING 4'-[[4-METHYL-6-(1-METHYL-1H-BENZIMIDAZOL-2-YL)-2-PROPYL-1H-BENZIMIDAZOL-1YL]METHYL]BIPHENYL-2-CARBOXYLIC ACID (TELMISARTAN) | ZENTIVA A.S. (CZ) | 2009-01-15 | — | — | WO | disclosed |
| EP-1805146-A4 | PROCESS FOR PREPARING TELMISARTAN | REDDYS LAB LTD DR (IN) | 2009-01-14 | — | — | EP | disclosed |
| US-20070287840-A1 | Process for Preparing Telmisartan | DR. REDDY'S LABORATORIES LIMITED (IN) | 2007-12-13 | — | — | US | disclosed |
| US-20070287840-A1 | Process for Preparing Telmisartan | DR. REDDY'S LABORATORIES LIMITED (IN) | 2007-12-13 | — | — | US | disclosed |
| EP-1805146-A2 | PROCESS FOR PREPARING TELMISARTAN | Dr. Reddy's Laboratories Ltd. (IN) | 2007-07-11 | — | — | EP | disclosed |
| WO-2006136916-A2 | SUBSTANTIALLY PURE MICRONIZED PARTICLES OF TELMISARTAN AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | GLENMARK PHARMACEUTICALS LIMITED (US) | 2006-12-28 | — | — | WO | disclosed |
| WO-2006136916-A2 | SUBSTANTIALLY PURE MICRONIZED PARTICLES OF TELMISARTAN AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | GLENMARK PHARMACEUTICALS LIMITED (US) | 2006-12-28 | — | — | WO | disclosed |
| US-20060211866-A1 | Process for the preparation of angiotensin receptor blockers and intermediates thereof | GLENMARK PHARMACEUTICALS LIMITED (IN) | 2006-09-21 | — | — | US | disclosed |
| WO-2006044754-A2 | PROCESS FOR PREPARING TELMISARTAN | DR. REDDY'S LABORATORIES LTD. (IN) | 2006-04-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110201621-A1 | ANGIOTENSIN II RECEPTOR ANTAGONISTS | AGTR1, AGTR2, REN | AGTR1 1/4885PPARG 1454/4885AGTR2 2/4885 |
| US-20060211866-A1 | Process for the preparation of angiotensin receptor blockers and intermediates thereof | AGTR1, AGTR2, BDKRB1 | AGTR1 1/4885PPARG 741/4885AGTR2 2/4885 |
| US-20070287840-A1 | Process for Preparing Telmisartan | AGT, TTR, REN | AGTR1 4/4885PPARG 2394/4885AGTR2 10/4885 |
| US-20100144810-A1 | ANGIOTENSIN II RECEPTOR ANTAGONISTS | AGTR1, AGTR2, REN | AGTR1 1/4885PPARG 882/4885AGTR2 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.