Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 5/20 | 0.84 |
| ▸ | AGTR1 | P30556 | 4/20 | 0.84 |
| ▸ | AGTR2 | P50052 | 3/20 | 0.84 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.84 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.84 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.84 |
| ▸ | USP2 | O75604 | 1/20 | 0.84 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.84 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.84 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.84 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.84 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.84 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.84 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.84 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.84 |
| ▸ | ACE | P12821 | 1/20 | 0.84 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.84 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.84 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.84 |
| ▸ | PDE4A | P27815 | 1/20 | 0.84 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19432748 | 0.95 | PPARG (0.81) | PPARGAGTR1AGTR2KDM4EABCC3 | |
| SCHEMBL255337 | 0.94 | AGTR1 (0.84) | PPARGAGTR1AGTR2KDM4EABCC3 | |
| Hydrochloric Acid SCHEMBL1203765 | 0.93 | PPARG (0.78) | PPARGAGTR1AGTR2KDM4EABCC3 | |
| SCHEMBL17948609 | 0.93 | PPARG (0.84) | PPARGAGTR1AGTR2KDM4EABCC3 | |
| SCHEMBL10021554 | 0.92 | AGTR1 (0.80) | PPARGAGTR1AGTR2KDM4EABCC3 | |
| SCHEMBL170874 | 0.92 | PPARG (0.80) | PPARGAGTR1AGTR2KDM4EABCC3 | |
| SCHEMBL13138015 | 0.91 | PPARG (0.88) | PPARGAGTR1AGTR2KDM4EABCC3 | |
| SCHEMBL17946015 | 0.91 | PPARG (0.88) | PPARGAGTR1AGTR2KDM4EABCC3 | |
| Telmisartan SCHEMBL2122886 | 0.91 | AGTR1 (1.00) | PPARGAGTR1AGTR2KDM4EABCC3 | |
| Telmisartan SCHEMBL4464 | 0.91 | AGTR1 (1.00) | PPARGAGTR1AGTR2KDM4EABCC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8598202-B2 | Aryl-hydroxyethylamino-pyrimidines and triazines as modulators of fatty acid amide hydrolase | JANSSEN PHARMACEUTICA NV (BE) | 2013-12-03 | — | — | US | claimed |
| EP-2254415-B1 | ARYL-HYDROXYETHYLAMINO-PYRIMIDINES AND TRIAZINES AS MODULATORS OF FATTY ACID AMIDE HYDROLASE | JANSSEN PHARMACEUTICA NV (BE) | 2013-01-23 | — | — | EP | claimed |
| US-20090264429-A1 | Aryl - Hydroxyethylamino - Pyrimidines and Triazines as Modulators of Fatty Acid amide Hydrolase | JANSSEN PHARMACEUTICA NV (BE) | 2009-10-22 | — | — | US | claimed |
| US-8598202-B2 | Aryl-hydroxyethylamino-pyrimidines and triazines as modulators of fatty acid amide hydrolase | JANSSEN PHARMACEUTICA NV (BE) | 2013-12-03 | — | — | US | disclosed |
| EP-2254415-B1 | ARYL-HYDROXYETHYLAMINO-PYRIMIDINES AND TRIAZINES AS MODULATORS OF FATTY ACID AMIDE HYDROLASE | JANSSEN PHARMACEUTICA NV (BE) | 2013-01-23 | — | — | EP | disclosed |
| EP-1719766-B1 | A process for the preparation of telmisartan | DIPHARMA FRANCIS SRL (IT) | 2010-11-03 | — | — | EP | disclosed |
| US-7692027-B2 | Process for the preparation of telmisartan | DIPHARMA S.P.A. (IT) | 2010-04-06 | — | — | US | disclosed |
| WO-2010018441-A2 | AN IMPROVED PROCESS FOR THE PREPARATION OF SUBSTANTIALLY PURE TELMISARTAN | CADILA PHARMACEUTICALS LTD. (IN) | 2010-02-18 | — | — | WO | disclosed |
| EP-2123648-A1 | A process for the preparation of Telmisartan. | Chemo Ibérica, S.A. (ES) | 2009-11-25 | — | — | EP | disclosed |
| US-20090264429-A1 | Aryl - Hydroxyethylamino - Pyrimidines and Triazines as Modulators of Fatty Acid amide Hydrolase | JANSSEN PHARMACEUTICA NV (BE) | 2009-10-22 | — | — | US | disclosed |
| US-20060264644-A1 | Process for the preparation of telmisartan | DIPHARMA S.P.A. (IT) | 2006-11-23 | — | — | US | disclosed |
| EP-1719766-A2 | A process for the preparation of telmisartan | Dipharma S.p.A. (IT) | 2006-11-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090264429-A1 | Aryl - Hydroxyethylamino - Pyrimidines and Triazines as Modulators of Fatty Acid amide Hydrolase | FAAH, FAAH2, HRH2 | PPARG 115/4885AGTR1 2561/4885AGTR2 2246/4885 |
| US-20060264644-A1 | Process for the preparation of telmisartan | AGT, REN, AGTR1 | PPARG 2556/4885AGTR1 3/4885AGTR2 5/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.