SCHEMBL25535211

SCHEMBL25535211

c1ccc(-c2ccc(-c3cc(-c4ccc5sc6ccccc6c5c4)nc(-c4ccc(-c5ccc6c(c5)-c5ccccc5C6(c5ccccc5)c5ccccc5)c5ccccc45)n3)cc2)cc1

nearest known ligand 0.32

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
PIM3 Q86V86 1/20 0.32
MEN1 O00255 4/20 0.32
MAPT P10636 4/20 0.32
KMT2A Q03164 4/20 0.32
ALDH1A1 P00352 3/20 0.32
HPGD P15428 3/20 0.32
KDM4E B2RXH2 3/20 0.31
LMNA P02545 3/20 0.31
GLA P06280 1/20 0.31
PDK2 Q15119 1/20 0.31
OPRK1 P41145 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25534915 0.95 TDP1 (0.32) PIM3MEN1MAPTKMT2AALDH1A1
SCHEMBL25535205 0.94 MAPT (0.32) MEN1MAPTKMT2AALDH1A1HPGD
SCHEMBL25534990 0.92 MEN1 (0.34) MEN1MAPTKMT2AALDH1A1HPGD
SCHEMBL25535073 0.90 MEN1 (0.33) PIM3MEN1MAPTKMT2AALDH1A1
SCHEMBL25535135 0.90 MEN1 (0.34) PIM3MEN1MAPTKMT2AALDH1A1
SCHEMBL25534906 0.89 ALDH1A1 (0.32) MEN1MAPTKMT2AALDH1A1HPGD
SCHEMBL20647394 0.89 MEN1 (0.33) PIM3MEN1MAPTKMT2AALDH1A1
SCHEMBL20647404 0.89 MEN1 (0.33) PIM3MEN1MAPTKMT2AALDH1A1
SCHEMBL25535189 0.89 MEN1 (0.39) MEN1MAPTKMT2AALDH1A1HPGD
SCHEMBL25535202 0.89 ALOX5 (0.39) MEN1MAPTKMT2AALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230167072-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, ORGANIC ELECTROLUMINESCENT ELEMENT, AND ELECTRONIC DEVICE IDEMITSU KOSAN CO.,LTD. (JP) 2023-06-01 US disclosed
US-20230167072-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, ORGANIC ELECTROLUMINESCENT ELEMENT, AND ELECTRONIC DEVICE IDEMITSU KOSAN CO.,LTD. (JP) 2023-06-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230167072-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, ORGANIC ELECTROLUMINESCENT ELEMENT, AND ELECTRONIC DEVICE PIEZO1, LEF1, L1CAM PIM3 3340/4885MEN1 267/4885MAPT 1595/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.