Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHBG | P04278 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | MDH1 | P40925 | 1/20 | 0.33 |
| ▸ | MDH2 | P40926 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | USP2 | O75604 | 3/20 | 0.33 |
| ▸ | ESR1 | P03372 | 3/20 | 0.33 |
| ▸ | TP53 | P04637 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.33 |
| ▸ | PGR | P06401 | 2/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.33 |
| ▸ | DRD1 | P21728 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3386524 | 0.77 | SHBG (0.57) | SHBGCYP3A4SMN1; SMN2HIF1ACYP2D6 | |
| SCHEMBL2037077 | 0.76 | SHBG (0.61) | SHBGCYP3A4SMN1; SMN2HIF1ACYP2D6 | |
| SCHEMBL9081437 | 0.76 | SHBG (0.61) | SHBGCYP3A4SMN1; SMN2HIF1ACYP2D6 | |
| SCHEMBL10515698 | 0.75 | SHBG (0.67) | SHBGCYP3A4SMN1; SMN2HIF1ACYP2D6 | |
| SCHEMBL10736138 | 0.74 | SHBG (0.59) | SHBGCYP3A4SMN1; SMN2HIF1ACYP2D6 | |
| Potassium Ion SCHEMBL10521541 | 0.74 | SHBG (0.59) | SHBGCYP3A4SMN1; SMN2HIF1ACYP2D6 | |
| SCHEMBL6537145 | 0.73 | SHBG (0.59) | SHBGCYP3A4SMN1; SMN2HIF1ACYP2D6 | |
| SCHEMBL10565613 | 0.73 | SHBG (0.53) | SHBGCYP3A4SMN1; SMN2HIF1ACYP2D6 | |
| SCHEMBL8768818 | 0.73 | SHBG (0.64) | SHBGCYP3A4SMN1; SMN2HIF1ACYP2D6 | |
| SCHEMBL8743939 | 0.72 | SHBG (0.52) | SHBGCYP3A4SMN1; SMN2MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230159491-A1 | Antimicrobial Compounds and Methods | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2023-05-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230159491-A1 | Antimicrobial Compounds and Methods | MPO, NISCH, RPN2 | SHBG 4307/4885CYP3A4 2721/4885SMN1; SMN2 4817/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.