Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25532038 | 0.90 | TSHR (0.47) | TSHRKDM4ELMNAHPGDMEN1 | |
| SCHEMBL21311727 | 0.89 | TSHR (0.46) | TSHRKDM4ELMNAHPGDMEN1 | |
| SCHEMBL18306913 | 0.88 | MEN1 (0.45) | TSHRKDM4ELMNAHPGDMEN1 | |
| SCHEMBL22858759 | 0.87 | TSHR (0.70) | TSHRKDM4ELMNAHPGDMEN1 | |
| SCHEMBL23729451 | 0.86 | TSHR (0.51) | TSHRKDM4ELMNAHPGDMEN1 | |
| SCHEMBL21947703 | 0.85 | TSHR (0.73) | TSHRKDM4ELMNAHPGDMEN1 | |
| SCHEMBL17874808 | 0.85 | MEN1 (0.47) | TSHRKDM4ELMNAHPGDMEN1 | |
| SCHEMBL25834703 | 0.85 | MEN1 (0.47) | TSHRKDM4ELMNAHPGDMEN1 | |
| SCHEMBL26034458 | 0.84 | TSHR (0.41) | TSHRKDM4ELMNAHPGDMEN1 | |
| SCHEMBL12834880 | 0.83 | TSHR (0.59) | TSHRKDM4ELMNAHPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230158169-A1 | LINKERS FOR IMPROVING THE STABILITY OF BIOCONJUGATES AND THE SELECTIVITY OF PAYLOAD RELEASE | AUDAX PRIVATE DEBT LLC, AS AGENT | 2023-05-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230158169-A1 | LINKERS FOR IMPROVING THE STABILITY OF BIOCONJUGATES AND THE SELECTIVITY OF PAYLOAD RELEASE | CTSA, CTSS, CTSV | TSHR 1373/4885KDM4E 2158/4885LMNA 659/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.