SCHEMBL2553763

SCHEMBL2553763

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nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRP O00591 2/20 0.46
GABRD O14764 2/20 0.46
GABRA1 P14867 2/20 0.46
GABRB1 P18505 2/20 0.46
GABRG2 P18507 2/20 0.46
GABRB3 P28472 2/20 0.46
GABRA5 P31644 2/20 0.46
GABRA3 P34903 2/20 0.46
GABRA2 P47869 2/20 0.46
GABRB2 P47870 2/20 0.46
GABRA4 P48169 2/20 0.46
GABRE P78334 2/20 0.46
GABRA6 Q16445 2/20 0.46
GABRG1 Q8N1C3 2/20 0.46
GABRG3 Q99928 2/20 0.46
GABRQ Q9UN88 2/20 0.46
TSHR P16473 3/20 0.38
TP53 P04637 1/20 0.38
EGLN1 Q9GZT9 1/20 0.38
EGLN3 Q9H6Z9 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29956544 0.90 GABRP (0.50) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL11218751 0.84 GABRP (0.48) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL4847645 0.77 TP53 (0.30) TP53
SCHEMBL11574314 0.70 TGFBR1 (0.33) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL26617402 0.69
SCHEMBL7536760 0.69
SCHEMBL1789373 0.69 GABRP (0.56) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL7138872 0.69 GABRP (0.56) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL2413101 0.69 GABRP (0.56) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL10499395 0.69 GABRP (0.50) GABRPGABRDGABRA1GABRB1GABRG2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3924166-B1 COREACTIVE THREE-DIMENSIONAL PRINTING OF PARTS PPG IND OHIO INC (US) 2024-04-24 EP disclosed
EP-4349601-A2 COREACTIVE THREE-DIMENSIONAL PRINTING OF PARTS PPG Industries Ohio, Inc. (US) 2024-04-10 EP disclosed
CN-117183327-A Co-reactive three-dimensional printing of parts PPG工业俄亥俄公司 2023-12-08 CN disclosed
US-20220126516-A1 COREACTIVE THREE-DIMENSIONAL PRINTING OF PARTS PPG INDUSTRIES OHIO, INC. (US) 2022-04-28 US disclosed
CN-113661046-A Co-reactive three-dimensional printing of parts PPG工业俄亥俄公司 2021-11-16 CN disclosed
EP-3257890-B1 CROSSLINKABLE COMPOSITION ALLNEX NETHERLANDS BV (NL) 2021-06-02 EP disclosed
EP-3257890-A1 CROSSLINKABLE COMPOSITION Allnex Netherlands B.V. (NL) 2017-12-20 EP disclosed
EP-2985308-B1 CROSSLINKABLE COMPOSITION ALLNEX NETHERLANDS BV (NL) 2017-07-19 EP disclosed
US-9534081-B2 Crosslinkable composition crosslinkable with a latent base catalyst NUPLEX RESINS B.V. (NL) 2017-01-03 US disclosed
EP-2556106-B1 CROSSLINKABLE COMPOSITION CROSSLINKABLE WITH A LATENT BASE CATALYST NUPLEX RESINS BV (NL) 2016-08-10 EP disclosed
US-20130210986-A1 CROSSLINKABLE COMPOSITION CROSSLINKABLE WITH A LATENT BASE CATALYST NUPLEX RESINS B.V. (NL) 2013-08-15 US disclosed
WO-2013113642-A1 REPAIR PROCESS AND PRIMER COMPOSITION AKZO NOBEL COATINGS INTERNATIONAL B.V. (NL) 2013-08-08 WO disclosed
US-20130053505-A1 CROSSLINKABLE COMPOSITION CROSSLINKABLE WITH A LATENT BASE CATALYST NUPLEX RESINS B.V. (NL) 2013-02-28 US disclosed
US-20130041091-A1 CROSSLINKABLE COMPOSITION CROSSLINKABLE WITH A LATENT BASE CATALYST NUPLEX RESINS B.V. (NL) 2013-02-14 US disclosed
EP-2556106-A1 CROSSLINKABLE COMPOSITION CROSSLINKABLE WITH A LATENT BASE CATALYST Nuplex Resins B.V. (NL) 2013-02-13 EP disclosed
EP-2556107-A1 CROSSLINKABLE COMPOSITION CROSSLINKABLE WITH A LATENT BASE CATALYST Nuplex Resins B.V. (NL) 2013-02-13 EP disclosed
EP-2556108-A1 CROSSLINKABLE COMPOSITION CROSSLINKABLE WITH A LATENT BASE CATALYST Nuplex Resins B.V. (NL) 2013-02-13 EP disclosed
WO-2011124663-A1 CROSSLINKABLE COMPOSITION CROSSLINKABLE WITH A LATENT BASE CATALYST NUPLEX RESINS B.V. (NL) 2011-10-13 WO disclosed
WO-2011124665-A1 CROSSLINKABLE COMPOSITION CROSSLINKABLE WITH A LATENT BASE CATALYST NUPLEX RESINS B.V. (NL) 2011-10-13 WO disclosed
WO-2011124664-A1 CROSSLINKABLE COMPOSITION CROSSLINKABLE WITH A LATENT BASE CATALYST NUPLEX RESINS B.V. (NL) 2011-10-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130041091-A1 CROSSLINKABLE COMPOSITION CROSSLINKABLE WITH A LATENT BASE CATALYST ARL1, ASH2L, COL1A1 GABRP 4007/4885GABRD 4691/4885GABRA1 3896/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.