Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | ATF4 | P18848 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17658518 | 0.90 | LMNA (0.72) | LMNAATF4KMT2AMEN1L3MBTL1 | |
| SCHEMBL12629118 | 0.90 | LMNA (0.72) | LMNAATF4KMT2AMEN1L3MBTL1 | |
| SCHEMBL19538657 | 0.87 | KMT2A (0.72) | LMNAATF4KMT2AMEN1L3MBTL1 | |
| SCHEMBL25539447 | 0.86 | KMT2A (0.66) | LMNAATF4KMT2AMEN1L3MBTL1 | |
| SCHEMBL4033699 | 0.86 | ATF4 (0.81) | LMNAATF4KMT2AHPGDHTT | |
| SCHEMBL5123998 | 0.86 | POLB (0.62) | LMNAATF4KMT2AMEN1L3MBTL1 | |
| SCHEMBL3456287 | 0.86 | KMT2A (0.73) | LMNAKMT2AMEN1L3MBTL1SMN1; SMN2 | |
| SCHEMBL25540412 | 0.85 | KMT2A (0.77) | LMNAATF4KMT2AMEN1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL19692584 | 0.85 | ATF4 (0.79) | LMNAATF4KMT2AHPGDHTT | |
| SCHEMBL19134248 | 0.83 | LMNA (0.63) | LMNAATF4KMT2AMEN1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230165848-A1 | CHEMICAL COMPOUNDS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2023-06-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230165848-A1 | CHEMICAL COMPOUNDS | ATF4, XBP1, EIF2B5 | LMNA 470/4885ATF4 1/4885KMT2A 3707/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.