Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.66 |
| ▸ | MEN1 | O00255 | 4/20 | 0.66 |
| ▸ | POLB | P06746 | 2/20 | 0.66 |
| ▸ | MAPT | P10636 | 1/20 | 0.66 |
| ▸ | RECQL | P46063 | 1/20 | 0.66 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | ATF4 | P18848 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | ALPL | P05186 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25538362 | 0.86 | LMNA (0.59) | KMT2AMEN1LMNAATF4L3MBTL1 | |
| SCHEMBL4033699 | 0.84 | ATF4 (0.81) | KMT2ALMNAATF4RAB9AHPGD | |
| SCHEMBL5123998 | 0.83 | POLB (0.62) | KMT2AMEN1POLBLMNAATF4 | |
| Hydrochloric Acid SCHEMBL19692584 | 0.83 | ATF4 (0.79) | KMT2ALMNAATF4RAB9AHPGD | |
| SCHEMBL25540882 | 0.81 | KMT2A (0.56) | KMT2AMEN1POLBMAPTRECQL | |
| SCHEMBL2105226 | 0.81 | LMNA (0.56) | KMT2AMEN1POLBLMNAATF4 | |
| SCHEMBL25540412 | 0.81 | KMT2A (0.77) | KMT2AMEN1LMNAATF4SMN1; SMN2 | |
| SCHEMBL9611332 | 0.78 | LMNA (0.54) | KMT2AMEN1LMNAATF4L3MBTL1 | |
| SCHEMBL19692630 | 0.78 | ATF4 (0.59) | KMT2AMEN1MAPTLMNAATF4 | |
| SCHEMBL25540101 | 0.77 | POLB (0.56) | KMT2AMEN1POLBMAPTRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230165848-A1 | CHEMICAL COMPOUNDS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2023-06-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230165848-A1 | CHEMICAL COMPOUNDS | ATF4, XBP1, EIF2B5 | KMT2A 3707/4885MEN1 2482/4885POLB 3320/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.