Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6134967 | 0.90 | HSD11B1 (0.40) | HSD11B1 | |
| SCHEMBL5036242 | 0.84 | ATM (0.32) | HSD11B1 | |
| SCHEMBL23125323 | 0.82 | CHRNB2 (0.32) | — | |
| SCHEMBL71966 | 0.73 | CHRM2 (0.49) | HSD11B1 | |
| SCHEMBL610766 | 0.72 | VNN1 (0.37) | HSD11B1 | |
| SCHEMBL23404413 | 0.72 | VNN1 (0.37) | HSD11B1 | |
| SCHEMBL4335026 | 0.72 | VNN1 (0.37) | HSD11B1 | |
| SCHEMBL27006946 | 0.72 | VNN1 (0.37) | HSD11B1 | |
| SCHEMBL5501263 | 0.70 | RAB9A (0.33) | — | |
| SCHEMBL17057328 | 0.70 | RAB9A (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011121223-A1 | 6-(ALKYL- OR CYCLOALKYL-TRIAZOLOPYRIDAZINE-SULFANYL) BENZOTHIAZOLE DERIVATIVES: PREPARATION, APPLICATION AS MEDICAMENTS AND USE AS MET INHIBITORS | SANOFI-AVENTIS (FR) | 2011-10-06 | — | — | WO | disclosed |