SCHEMBL25544989

SCHEMBL25544989

N#Cc1ccc(-c2ccc(N(c3ccc(-c4ccc5c(c4)oc4cc(C#N)ccc45)cc3)c3ccc(-c4ccc5c(c4)oc4cc(C#N)ccc45)cc3)cc2)cc1

nearest known ligand 0.42

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
PGR P06401 3/20 0.42
TNKS O95271 1/20 0.38
MMP3 P08254 1/20 0.37
KIF11 P52732 3/20 0.36
MAP4K4 O95819 1/20 0.35
HRH3 Q9Y5N1 6/20 0.35
IDO1 P14902 2/20 0.35
CYP3A4 P08684 1/20 0.35
MAPT P10636 1/20 0.35
ALOX15 P16050 1/20 0.35
CNR1 P21554 1/20 0.35
CASP1 P29466 1/20 0.35
CNR2 P34972 1/20 0.35
CASP7 P55210 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
NOTUM Q6P988 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25544858 1.00 PGR (0.42) PGRTNKSMMP3KIF11MAP4K4
SCHEMBL25544849 0.93 IDO1 (0.38) PGRTNKSIDO1CYP3A4
SCHEMBL25544984 0.93 IDO1 (0.38) PGRTNKSIDO1CYP3A4
SCHEMBL25544993 0.93 PGR (0.37) PGRTNKSMMP3KIF11MAP4K4
SCHEMBL26289024 0.93 PGR (0.37) PGRTNKSMMP3KIF11MAP4K4
SCHEMBL25544996 0.90 PGR (0.35) PGRTNKSIDO1CYP3A4MAPT
SCHEMBL25544861 0.89 PGR (0.35) PGRTNKSHRH3IDO1MAPT
SCHEMBL25544841 0.89 IDO1 (0.37) PGRTNKSIDO1CYP3A4MAPT
SCHEMBL17936235 0.84 TNKS (0.41) PGRTNKSMMP3CYP3A4MAPT
SCHEMBL14295624 0.82 TNKS (0.48) PGRTNKSMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230301181-A1 TERTIARY AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME LAPTO CO., LTD. (KR) 2023-09-21 US disclosed
EP-4183784-A1 TERTIARY AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME Lapto Co., Ltd. (KR) 2023-05-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230301181-A1 TERTIARY AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME SAT1, FTO, SETDB1 PGR 3943/4885TNKS 617/4885MMP3 4768/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.