SCHEMBL25544849

SCHEMBL25544849

N#Cc1ccc2c(c1)oc1cc(-c3ccc(N(c4ccccc4)c4ccc(-c5ccc6c(c5)oc5cc(C#N)ccc56)cc4)cc3)ccc12

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 2/20 0.38
TNKS O95271 1/20 0.38
PGR P06401 2/20 0.37
MMP12 P39900 1/20 0.34
MMP13 P45452 1/20 0.34
GABRA1 P14867 1/20 0.34
GABRG2 P18507 1/20 0.34
GABRB3 P28472 1/20 0.34
GABRA5 P31644 1/20 0.34
GABRA3 P34903 1/20 0.34
TDO2 P48775 1/20 0.33
ACLY P53396 1/20 0.33
PTGDR2 Q9Y5Y4 1/20 0.33
GSK3B P49841 2/20 0.33
MYC P01106 1/20 0.33
KDM1A O60341 1/20 0.32
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
ABCG2 Q9UNQ0 1/20 0.32
ALDH1A1 P00352 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25544984 0.97 IDO1 (0.38) IDO1TNKSPGRMMP12MMP13
SCHEMBL25544858 0.93 PGR (0.42) IDO1TNKSPGRCYP3A4
SCHEMBL25544989 0.93 PGR (0.42) IDO1TNKSPGRCYP3A4
SCHEMBL25544856 0.90 IDO1 (0.40) IDO1TNKSTDO2KDM1AMEN1
SCHEMBL25544993 0.89 PGR (0.37) IDO1TNKSPGRTDO2ALDH1A1
SCHEMBL26289024 0.89 PGR (0.37) IDO1TNKSPGRTDO2ALDH1A1
SCHEMBL17936235 0.89 TNKS (0.41) TNKSPGRGABRA1GABRG2GABRB3
SCHEMBL10110694 0.87 MMP12 (0.41) PGRMMP12MMP13MEN1KMT2A
SCHEMBL25544996 0.86 PGR (0.35) IDO1TNKSPGRTDO2MEN1
SCHEMBL14295630 0.85 TNKS (0.47) TNKSPGRMMP12MMP13GABRA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230301181-A1 TERTIARY AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME LAPTO CO., LTD. (KR) 2023-09-21 US disclosed
EP-4183784-A1 TERTIARY AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME Lapto Co., Ltd. (KR) 2023-05-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230301181-A1 TERTIARY AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME SAT1, FTO, SETDB1 IDO1 930/4885TNKS 617/4885PGR 3943/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.