SCHEMBL25544993

SCHEMBL25544993

N#Cc1cc(C#N)cc(-c2ccc(N(c3ccc(-c4ccc5c(c4)oc4cc(C#N)ccc45)cc3)c3ccc(-c4ccc5c(c4)oc4cc(C#N)ccc45)cc3)cc2)c1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PGR P06401 3/20 0.37
IDO1 P14902 2/20 0.33
TNKS O95271 1/20 0.33
XDH P47989 3/20 0.32
SLC22A12 Q96S37 3/20 0.32
MAPT P10636 2/20 0.31
SMN1; SMN2 Q16637 2/20 0.31
CYP3A4 P08684 1/20 0.31
ALOX15 P16050 1/20 0.31
CNR1 P21554 1/20 0.31
CASP1 P29466 1/20 0.31
CNR2 P34972 1/20 0.31
CASP7 P55210 1/20 0.31
TDO2 P48775 1/20 0.31
MMP3 P08254 1/20 0.31
HRH3 Q9Y5N1 1/20 0.31
MAP4K4 O95819 1/20 0.31
KIF11 P52732 1/20 0.31
NOS3 P29474 1/20 0.31
NOS1 P29475 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26289024 0.94 PGR (0.37) PGRIDO1TNKSXDHSLC22A12
SCHEMBL25544858 0.93 PGR (0.42) PGRIDO1TNKSMAPTSMN1; SMN2
SCHEMBL25544989 0.93 PGR (0.42) PGRIDO1TNKSMAPTSMN1; SMN2
SCHEMBL25544984 0.89 IDO1 (0.38) PGRIDO1TNKSXDHSLC22A12
SCHEMBL25544849 0.89 IDO1 (0.38) PGRIDO1TNKSCYP3A4TDO2
SCHEMBL25544996 0.86 PGR (0.35) PGRIDO1TNKSMAPTSMN1; SMN2
SCHEMBL25544861 0.85 PGR (0.35) PGRIDO1TNKSMAPTHRH3
SCHEMBL25544847 0.82 IDO1 (0.36) IDO1TNKSMAPTSMN1; SMN2ALOX15
SCHEMBL25544841 0.82 IDO1 (0.37) PGRIDO1TNKSMAPTSMN1; SMN2
SCHEMBL23328469 0.81 TNKS (0.42) PGRTNKSMAPTSMN1; SMN2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230301181-A1 TERTIARY AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME LAPTO CO., LTD. (KR) 2023-09-21 US disclosed
EP-4183784-A1 TERTIARY AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME Lapto Co., Ltd. (KR) 2023-05-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230301181-A1 TERTIARY AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME SAT1, FTO, SETDB1 PGR 3943/4885IDO1 930/4885TNKS 617/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.