Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.38 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ACACB | O00763 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | DRD1 | P21728 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25549614 | 0.82 | AOC3 (0.40) | ADRB3AOC3ALDH1A1MAPT | |
| SCHEMBL18290856 | 0.81 | LMNA (0.50) | MEN1KMT2AADRB3GAAMAPK1 | |
| SCHEMBL11251522 | 0.79 | AOC3 (0.58) | MEN1KMT2AGAAMAPK1L3MBTL1 | |
| SCHEMBL18290854 | 0.79 | KMT2A (0.45) | MEN1KMT2AGAAMAPK1ALOX15 | |
| SCHEMBL6285397 | 0.78 | TAAR1 (0.53) | MEN1KMT2AADRB3MAPK1ALOX15 | |
| SCHEMBL25550486 | 0.77 | AOC3 (0.39) | MEN1KMT2AGAAMAPK1ALOX15 | |
| SCHEMBL28510777 | 0.76 | NQO1 (0.52) | MEN1KMT2AMAPK1L3MBTL1LMNA | |
| SCHEMBL13859551 | 0.76 | CYP17A1 (0.45) | MEN1KMT2AGAAMAPK1ALOX15 | |
| SCHEMBL11530059 | 0.75 | AOC3 (0.53) | MEN1KMT2AGAAAOC3ALDH1A1 | |
| SCHEMBL16673700 | 0.75 | AOC3 (0.53) | MEN1KMT2AAOC3HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118103368-A | EIF4E inhibitors and uses thereof | 皮克医疗公司 | 2024-05-28 | — | — | CN | disclosed |
| US-20230150997-A1 | EIF4E INHIBITORS AND USES THEREOF | PIC Therapeutics, Inc. | 2023-05-18 | — | — | US | disclosed |
| CN-112321440-B | Amino phenyl ketone compound and preparation method and application thereof | 南方医科大学 | 2021-09-24 | — | — | CN | disclosed |
| CN-112321440-A | Amino phenyl ketone compound and preparation method and application thereof | 南方医科大学 | 2021-02-05 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230150997-A1 | EIF4E INHIBITORS AND USES THEREOF | EIF4E, EIF4EBP1, EIF4A1 | MEN1 2104/4885KMT2A 1931/4885ADRB3 4856/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.