Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 3/20 | 0.40 |
| ▸ | ANPEP | P15144 | 1/20 | 0.34 |
| ▸ | LAP3 | P28838 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ADRB3 | P13945 | 5/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25545401 | 0.82 | MEN1 (0.40) | AOC3ALDH1A1MAPTADRB3 | |
| SCHEMBL11251522 | 0.79 | AOC3 (0.58) | AOC3ALDH1A1MAPT | |
| SCHEMBL28510777 | 0.76 | NQO1 (0.52) | MAPT | |
| SCHEMBL11530059 | 0.75 | AOC3 (0.53) | AOC3ALDH1A1MAPT | |
| SCHEMBL29861042 | 0.74 | CTSS (0.39) | AOC3ALDH1A1 | |
| SCHEMBL12197898 | 0.72 | ACHE (0.46) | AOC3ALDH1A1MAPT | |
| SCHEMBL18905326 | 0.71 | MEN1 (0.38) | — | |
| SCHEMBL12982600 | 0.71 | CYP19A1 (0.42) | AOC3ALDH1A1 | |
| SCHEMBL12243879 | 0.71 | AOC3 (0.53) | AOC3 | |
| SCHEMBL11901019 | 0.71 | CTSK (0.41) | AOC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230150997-A1 | EIF4E INHIBITORS AND USES THEREOF | PIC Therapeutics, Inc. | 2023-05-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230150997-A1 | EIF4E INHIBITORS AND USES THEREOF | EIF4E, EIF4EBP1, EIF4A1 | AOC3 4750/4885ANPEP 1942/4885LAP3 1968/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.