Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 6/20 | 0.36 |
| ▸ | FBP1 | P09467 | 1/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.33 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.33 |
| ▸ | DCK | P27707 | 2/20 | 0.33 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 2/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | PTGES | O14684 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25546022 | 0.92 | TRPV1 (0.35) | FBP1TRPV1DCKHTR2CHTR2B | |
| SCHEMBL25545564 | 0.90 | S1PR4 (0.35) | AAK1TLR7S1PR4HTR2CHTR2B | |
| SCHEMBL25545528 | 0.89 | FBP1 (0.43) | AAK1FBP1S1PR4DCKHTR2C | |
| SCHEMBL25545544 | 0.89 | S1PR4 (0.37) | FBP1TRPV1S1PR4HTR2CHTR2B | |
| SCHEMBL25545560 | 0.88 | HTT (0.40) | FBP1TLR7S1PR4DCKHTR2C | |
| SCHEMBL25545930 | 0.88 | ALDH1A1 (0.41) | AAK1ALDH1A1PTGS1PTGS2HTT | |
| SCHEMBL25545990 | 0.88 | FBP1 (0.42) | AAK1FBP1S1PR4DCKHTR2C | |
| SCHEMBL25546020 | 0.87 | TRPV1 (0.43) | FBP1TRPV1DCKHTR2CHTR2B | |
| SCHEMBL25545551 | 0.84 | FBP1 (0.43) | AAK1FBP1TLR7S1PR4ALDH1A1 | |
| SCHEMBL25545533 | 0.83 | AAK1 (0.36) | AAK1TRPV1TLR7S1PR4DCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230150997-A1 | EIF4E INHIBITORS AND USES THEREOF | PIC Therapeutics, Inc. | 2023-05-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230150997-A1 | EIF4E INHIBITORS AND USES THEREOF | EIF4E, EIF4EBP1, EIF4A1 | AAK1 1064/4885FBP1 735/4885TRPV1 4604/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.