Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 3/20 | 0.43 |
| ▸ | AAK1 | Q2M2I8 | 6/20 | 0.38 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.34 |
| ▸ | PI4KA | P42356 | 1/20 | 0.34 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.34 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.34 |
| ▸ | DCK | P27707 | 2/20 | 0.33 |
| ▸ | HTR2C | P28335 | 2/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25545990 | 0.98 | FBP1 (0.42) | FBP1AAK1S1PR4PIK3CDPIK3CA | |
| SCHEMBL25545551 | 0.95 | FBP1 (0.43) | FBP1AAK1S1PR4ALDH1A1PTGS1 | |
| SCHEMBL25545566 | 0.91 | FBP1 (0.43) | FBP1PIK3CDPIK3CAPIK3CBPI4KA | |
| SCHEMBL25545985 | 0.90 | FBP1 (0.40) | FBP1AAK1S1PR4DCKPTGS1 | |
| SCHEMBL25545988 | 0.90 | FBP1 (0.43) | FBP1AAK1S1PR4PTGS2HPGD | |
| SCHEMBL25545547 | 0.89 | AAK1 (0.36) | FBP1AAK1S1PR4DCKHTR2C | |
| SCHEMBL25545564 | 0.88 | S1PR4 (0.35) | AAK1S1PR4PIK3CDPIK3CAPIK3CB | |
| SCHEMBL25545925 | 0.88 | ALDH1A1 (0.42) | FBP1AAK1ALDH1A1PTGS1PTGS2 | |
| SCHEMBL25183737 | 0.87 | FBP1 (0.45) | FBP1PIK3CDPIK3CAPIK3CBPI4KA | |
| SCHEMBL25556402 | 0.86 | PTGS1 (0.42) | FBP1AAK1S1PR4PIK3CDPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230150997-A1 | EIF4E INHIBITORS AND USES THEREOF | PIC Therapeutics, Inc. | 2023-05-18 | — | — | US | disclosed |
| US-20230150997-A1 | EIF4E INHIBITORS AND USES THEREOF | PIC Therapeutics, Inc. | 2023-05-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230150997-A1 | EIF4E INHIBITORS AND USES THEREOF | EIF4E, EIF4EBP1, EIF4A1 | FBP1 735/4885AAK1 1064/4885S1PR4 3887/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.