Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 3/20 | 0.62 |
| ▸ | MAOB | P27338 | 3/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.61 |
| ▸ | MEN1 | O00255 | 8/20 | 0.61 |
| ▸ | MAPT | P10636 | 6/20 | 0.61 |
| ▸ | HTT | P42858 | 4/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.59 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.59 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.59 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.59 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.59 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.59 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.59 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.59 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.59 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.59 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2554058 | 0.88 | RAB9A (0.64) | MAOAMAOBKMT2AMEN1MAPT | |
| SCHEMBL10808167 | 0.83 | BAZ1A (0.79) | MAOAMAOBKMT2AMEN1MAPT | |
| SCHEMBL10922701 | 0.83 | KMT2A (0.72) | MAOAMAOBKMT2AMEN1MAPT | |
| SCHEMBL2557289 | 0.83 | RAB9A (0.61) | KMT2AMEN1MAPTALDH1A1HDAC3 | |
| SCHEMBL2558907 | 0.83 | ABL1 (0.65) | MAOAKMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL2557829 | 0.83 | RAB9A (0.61) | KMT2AMEN1MAPTALDH1A1HDAC1 | |
| SCHEMBL2559105 | 0.83 | RAB9A (0.61) | MAOAKMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL10962764 | 0.82 | KMT2A (0.74) | MAOAMAOBKMT2AMEN1MAPT | |
| SCHEMBL2558995 | 0.82 | HDAC3 (0.57) | KMT2AMEN1MAPTHTTALDH1A1 | |
| SCHEMBL2562338 | 0.82 | RAB9A (0.63) | KMT2AMEN1MAPTHTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011130515-A1 | ARYLTHIAZOLYL PIPERIDINES AND RELATED COMPOUNDS AS MODULATORS OF SURVIVAL MOTOR NEURON (SMN) PROTEIN PRODUCTION | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2011-10-20 | — | — | WO | claimed |