Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19066945 | 0.85 | PRKCA (0.36) | — | |
| SCHEMBL24259200 | 0.78 | CYP1A2 (0.34) | — | |
| SCHEMBL3627165 | 0.78 | KDM4E (0.32) | KDM4EPKM | |
| SCHEMBL2965528 | 0.77 | GNAI3 (0.32) | — | |
| SCHEMBL29324533 | 0.76 | — | — | |
| SCHEMBL7732887 | 0.75 | SLC6A4 (0.33) | KDM4EPKM | |
| SCHEMBL21134598 | 0.75 | SLC6A4 (0.33) | KDM4EPKM | |
| SCHEMBL21134592 | 0.75 | SLC6A4 (0.33) | KDM4EPKM | |
| SCHEMBL19321833 | 0.75 | KDM1A (0.33) | — | |
| SCHEMBL26707552 | 0.75 | CYP1A2 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230159573-A1 | SMALL MOLECULE STAT PROTEIN DEGRADERS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2023-05-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230159573-A1 | SMALL MOLECULE STAT PROTEIN DEGRADERS | STAT1, STAT3, STAT5A | KDM4E 672/4885PKM 1851/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.