Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25216320 | 0.85 | USP2 (0.42) | RORCHDAC2USP30 | |
| SCHEMBL1855329 | 0.73 | SMN1; SMN2 (0.46) | NAMPT | |
| SCHEMBL19273133 | 0.72 | CYP11B2 (0.38) | NAMPTRORCHDAC2USP30 | |
| SCHEMBL23579280 | 0.72 | USP2 (0.44) | RORCHDAC2USP30 | |
| SCHEMBL12445300 | 0.71 | USP2 (0.46) | RORCHDAC2USP30 | |
| SCHEMBL27099789 | 0.71 | OPRM1 (0.44) | RORCUSP30 | |
| SCHEMBL30267043 | 0.71 | USP2 (0.41) | NAMPT | |
| SCHEMBL1848025 | 0.70 | HPGD (0.47) | — | |
| SCHEMBL1061211 | 0.70 | USP2 (0.45) | RORCHDAC2USP30 | |
| SCHEMBL25793602 | 0.70 | USP2 (0.41) | NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023097227-A1 | SMALL MOLECULE INHIBITORS OF KRAS MUTATED PROTEINS | MERCK SHARP & DOHME LLC (US) | 2023-06-01 | — | — | WO | disclosed |