SCHEMBL2555147

SCHEMBL2555147

CC1=CC(SC(=S)N(C)c2ccccc2)OC1=O

nearest known ligand 0.49

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
FAAH O00519 1/20 0.49
PHGDH O43175 1/20 0.49
MGLL Q99685 1/20 0.49
LMNA P02545 2/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
CA12 O43570 1/20 0.38
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
CA9 Q16790 1/20 0.38
ALDH1A1 P00352 1/20 0.36
LIPE Q05469 1/20 0.33
POLB P06746 2/20 0.32
KMT2A Q03164 1/20 0.32
MAOB P27338 1/20 0.32
PKM P14618 1/20 0.31
NPC1 O15118 1/20 0.31
RAB9A P51151 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2552988 0.68 RAB9A (0.40) LMNAL3MBTL1ALDH1A1LIPEPOLB
SCHEMBL134834 0.68 MGLL (1.00) FAAHPHGDHMGLLLMNAL3MBTL1
SCHEMBL9370061 0.68 MGLL (0.76) FAAHPHGDHMGLLLMNAL3MBTL1
SCHEMBL11746481 0.66 MGLL (0.73) FAAHPHGDHMGLLLMNAL3MBTL1
SCHEMBL9839811 0.65 MGLL (0.84) FAAHPHGDHMGLLLMNAL3MBTL1
SCHEMBL21312100 0.65 MGLL (0.70) FAAHPHGDHMGLLLMNAL3MBTL1
SCHEMBL27750501 0.65 MGLL (0.70) FAAHPHGDHMGLLLMNAL3MBTL1
SCHEMBL27657056 0.63 MGLL (0.68) FAAHPHGDHMGLLLMNAL3MBTL1
SCHEMBL28452213 0.63 MGLL (0.68) FAAHPHGDHMGLLLMNAL3MBTL1
SCHEMBL11850384 0.62 MGLL (0.66) FAAHPHGDHMGLLLMNAL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2562171-B1 GERMINATION-STIMULANT CARBAMATE DERIVATIVES AND PROCESS FOR PREPARATION THEREOF NAT UNIV CORP UNIV KOBE (JP) 2015-01-21 EP disclosed
EP-2562171-B1 GERMINATION-STIMULANT CARBAMATE DERIVATIVES AND PROCESS FOR PREPARATION THEREOF NAT UNIV CORP UNIV KOBE (JP) 2015-01-21 EP disclosed
US-8822383-B2 Germination-stimulant carbamate derivatives and process for preparation thereof NATIONAL UNIVERSITY CORPORATION KOBE UNIVERSITY (JP) 2014-09-02 US disclosed
US-8822383-B2 Germination-stimulant carbamate derivatives and process for preparation thereof NATIONAL UNIVERSITY CORPORATION KOBE UNIVERSITY (JP) 2014-09-02 US disclosed
US-8822383-B2 Germination-stimulant carbamate derivatives and process for preparation thereof NATIONAL UNIVERSITY CORPORATION KOBE UNIVERSITY (JP) 2014-09-02 US disclosed
US-20130085068-A1 GERMINATION-STIMULANT CARBAMATE DERIVATIVES AND PROCESS FOR PREPARATION THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-04-04 US disclosed
US-20130085068-A1 GERMINATION-STIMULANT CARBAMATE DERIVATIVES AND PROCESS FOR PREPARATION THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-04-04 US disclosed
EP-2562171-A1 GERMINATION-STIMULANT CARBAMATE DERIVATIVES AND PROCESS FOR PREPARATION THEREOF National University Corporation Kobe University (JP) 2013-02-27 EP disclosed
EP-2562171-A1 GERMINATION-STIMULANT CARBAMATE DERIVATIVES AND PROCESS FOR PREPARATION THEREOF National University Corporation Kobe University (JP) 2013-02-27 EP disclosed
WO-2011125714-A1 GERMINATION-STIMULANT CARBAMATE DERIVATIVES AND PROCESS FOR PREPARATION THEREOF 国立大学法人神戸大学 (JP) 2011-10-13 WO disclosed
WO-2011125714-A1 GERMINATION-STIMULANT CARBAMATE DERIVATIVES AND PROCESS FOR PREPARATION THEREOF 国立大学法人神戸大学 (JP) 2011-10-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130085068-A1 GERMINATION-STIMULANT CARBAMATE DERIVATIVES AND PROCESS FOR PREPARATION THEREOF FLT3, MYB, CHRM1 FAAH 1777/4885PHGDH 3972/4885MGLL 1829/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.