SCHEMBL2552988

SCHEMBL2552988

CC1=CC(OC(=O)N(C)c2ccccc2)OC1=O

nearest known ligand 0.40

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 3/20 0.40
SMN1; SMN2 Q16637 3/20 0.40
NFE2L2 Q16236 3/20 0.40
NPC1 O15118 2/20 0.40
MEN1 O00255 3/20 0.40
KMT2A Q03164 3/20 0.40
NPSR1 Q6W5P4 1/20 0.40
CHRNB2 P17787 1/20 0.39
CHRNB4 P30926 1/20 0.39
CHRNA3 P32297 1/20 0.39
CHRNA4 P43681 1/20 0.39
ALDH1A1 P00352 2/20 0.38
L3MBTL1 Q9Y468 3/20 0.37
LMNA P02545 2/20 0.37
LIPE Q05469 1/20 0.36
CHRM4 P08173 1/20 0.35
CHRM3 P20309 1/20 0.35
POLB P06746 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2552263 0.83 ALDH1A1 (0.40) SMN1; SMN2NFE2L2ALDH1A1LMNALIPE
SCHEMBL2555442 0.82 NPC1 (0.44) RAB9ASMN1; SMN2NFE2L2NPC1MEN1
SCHEMBL2552847 0.82 ALDH1A1 (0.46) RAB9ASMN1; SMN2NFE2L2NPC1MEN1
SCHEMBL2552478 0.81 GPBAR1 (0.39) NFE2L2LIPEPOLB
SCHEMBL2555151 0.81 LMNA (0.38) SMN1; SMN2NFE2L2MEN1KMT2AALDH1A1
SCHEMBL14714790 0.80 NFE2L2 (0.39) NFE2L2NPSR1L3MBTL1LMNAPOLB
SCHEMBL2552270 0.80 GPBAR1 (0.39) RAB9ANFE2L2MEN1KMT2ANPSR1
SCHEMBL15264430 0.76 NFE2L2 (0.44) SMN1; SMN2NFE2L2MEN1KMT2ANPSR1
SCHEMBL15264426 0.76 NFE2L2 (0.44) SMN1; SMN2NFE2L2MEN1KMT2ANPSR1
SCHEMBL2550943 0.71 LIPE (0.36) RAB9ASMN1; SMN2NPC1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2562171-B1 GERMINATION-STIMULANT CARBAMATE DERIVATIVES AND PROCESS FOR PREPARATION THEREOF NAT UNIV CORP UNIV KOBE (JP) 2015-01-21 EP claimed
US-8822383-B2 Germination-stimulant carbamate derivatives and process for preparation thereof NATIONAL UNIVERSITY CORPORATION KOBE UNIVERSITY (JP) 2014-09-02 US claimed
US-20130085068-A1 GERMINATION-STIMULANT CARBAMATE DERIVATIVES AND PROCESS FOR PREPARATION THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-04-04 US claimed
EP-2562171-A1 GERMINATION-STIMULANT CARBAMATE DERIVATIVES AND PROCESS FOR PREPARATION THEREOF National University Corporation Kobe University (JP) 2013-02-27 EP claimed
EP-2562171-B1 GERMINATION-STIMULANT CARBAMATE DERIVATIVES AND PROCESS FOR PREPARATION THEREOF NAT UNIV CORP UNIV KOBE (JP) 2015-01-21 EP disclosed
EP-2562171-B1 GERMINATION-STIMULANT CARBAMATE DERIVATIVES AND PROCESS FOR PREPARATION THEREOF NAT UNIV CORP UNIV KOBE (JP) 2015-01-21 EP disclosed
US-8822383-B2 Germination-stimulant carbamate derivatives and process for preparation thereof NATIONAL UNIVERSITY CORPORATION KOBE UNIVERSITY (JP) 2014-09-02 US disclosed
US-8822383-B2 Germination-stimulant carbamate derivatives and process for preparation thereof NATIONAL UNIVERSITY CORPORATION KOBE UNIVERSITY (JP) 2014-09-02 US disclosed
US-8822383-B2 Germination-stimulant carbamate derivatives and process for preparation thereof NATIONAL UNIVERSITY CORPORATION KOBE UNIVERSITY (JP) 2014-09-02 US disclosed
US-20130085068-A1 GERMINATION-STIMULANT CARBAMATE DERIVATIVES AND PROCESS FOR PREPARATION THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-04-04 US disclosed
US-20130085068-A1 GERMINATION-STIMULANT CARBAMATE DERIVATIVES AND PROCESS FOR PREPARATION THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-04-04 US disclosed
EP-2562171-A1 GERMINATION-STIMULANT CARBAMATE DERIVATIVES AND PROCESS FOR PREPARATION THEREOF National University Corporation Kobe University (JP) 2013-02-27 EP disclosed
WO-2011125714-A1 GERMINATION-STIMULANT CARBAMATE DERIVATIVES AND PROCESS FOR PREPARATION THEREOF 国立大学法人神戸大学 (JP) 2011-10-13 WO disclosed
WO-2011125714-A1 GERMINATION-STIMULANT CARBAMATE DERIVATIVES AND PROCESS FOR PREPARATION THEREOF 国立大学法人神戸大学 (JP) 2011-10-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130085068-A1 GERMINATION-STIMULANT CARBAMATE DERIVATIVES AND PROCESS FOR PREPARATION THEREOF FLT3, MYB, CHRM1 RAB9A 2722/4885SMN1; SMN2 4548/4885NFE2L2 4158/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.