SCHEMBL2555201

SCHEMBL2555201

OB(O)c1ccc(-c2ccc(OCc3ccccc3)cc2)cc1

nearest known ligand 0.90

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.59
CYP1A2 P05177 1/20 0.59
PTGS1 P23219 1/20 0.59
SLC6A2 P23975 1/20 0.59
CYP2C19 P33261 1/20 0.59
PTGS2 P35354 1/20 0.59
SLC6A3 Q01959 1/20 0.59
HIF1A Q16665 1/20 0.59
HDAC6 Q9UBN7 1/20 0.59
CA1 P00915 2/20 0.57
CA2 P00918 2/20 0.57
MGLL Q99685 1/20 0.57
GSTP1 P09211 2/20 0.54
MAOB P27338 4/20 0.53
GAA P10253 1/20 0.53
MAPT P10636 1/20 0.53
MAOA P21397 1/20 0.53
RAB9A P51151 1/20 0.53
SMN1; SMN2 Q16637 1/20 0.53
L3MBTL1 Q9Y468 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL142665 0.95 LMNA (0.66) LMNACYP1A2PTGS1SLC6A2CYP2C19
SCHEMBL15333100 0.90 CA1 (0.67) LMNACYP1A2PTGS1SLC6A2CYP2C19
SCHEMBL177615 0.87 APP (0.58) LMNACYP1A2PTGS1SLC6A2CYP2C19
SCHEMBL13903287 0.87 CYP1A2 (0.56) LMNACYP1A2PTGS1SLC6A2CYP2C19
SCHEMBL12420267 0.85 APP (0.54) LMNACYP1A2PTGS1SLC6A2CYP2C19
SCHEMBL197017 0.85 LMNA (0.72) LMNACYP1A2PTGS1SLC6A2CYP2C19
SCHEMBL6059706 0.84 CYP1A2 (0.66) LMNACYP1A2PTGS1SLC6A2CYP2C19
SCHEMBL9084030 0.84 DGAT1 (0.53) LMNACYP1A2PTGS1SLC6A2CYP2C19
SCHEMBL23495542 0.83 ENPP2 (0.61) CA1CA2MAOBMAPTRAB9A
SCHEMBL23483029 0.83 LMNA (0.69) LMNACYP1A2PTGS1SLC6A2CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed
US-11225655-B2 Bi-functional complexes and methods for making and using such complexes NUEVOLUTION A/S (DK) 2022-01-18 US disclosed
EP-3540059-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES Nuevolution A/S (DK) 2019-09-18 EP disclosed
EP-2558577-B1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION AS (DK) 2018-12-12 EP disclosed
US-9761804-B2 Oligomeric organic light emitting diode (OLED) materials containing multiple crosslinking functions LOMOX LIMITED (GB) 2017-09-12 US disclosed
US-9761804-B2 Oligomeric organic light emitting diode (OLED) materials containing multiple crosslinking functions LOMOX LIMITED (GB) 2017-09-12 US disclosed
US-20130281324-A1 BI-FUNCTINAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2013-10-24 US disclosed
EP-2558577-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES Nuevolution A/S (DK) 2013-02-20 EP disclosed
WO-2011127933-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2011-10-20 WO disclosed