SCHEMBL25552103

SCHEMBL25552103

C[C@@H](CCCCNC(=O)OCc1ccccc1)C(=O)N[C@H](C(=O)OCc1ccccc1)[C@@H](C)OCc1ccccc1

nearest known ligand 0.55

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 5/20 0.51
CPB1 P15086 1/20 0.50
CPB2 Q96IY4 1/20 0.50
HTT P42858 1/20 0.49
MAPT P10636 1/20 0.48
ANPEP P15144 1/20 0.48
TGM2 P21980 1/20 0.47
DPP8 Q6V1X1 1/20 0.47
DPP7 Q9UHL4 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25552109 0.90 ANPEP (0.58) FOLH1CPB1CPB2HTTANPEP
SCHEMBL25552205 0.89 CTSL (0.54) FOLH1CPB1CPB2HTTMAPT
SCHEMBL29832065 0.85 MAPT (0.57) FOLH1CPB1CPB2MAPT
SCHEMBL16575045 0.81 CPB1 (0.58) FOLH1CPB1CPB2HTTANPEP
SCHEMBL13471242 0.81 FOLH1 (0.62) FOLH1CPB1CPB2HTTTGM2
SCHEMBL9604544 0.81 FOLH1 (0.62) FOLH1CPB1CPB2HTTTGM2
SCHEMBL17250893 0.81 FOLH1 (0.62) FOLH1CPB1CPB2HTTTGM2
SCHEMBL31060114 0.81 CPB1 (0.53) FOLH1CPB1CPB2
SCHEMBL16575042 0.80 HTT (0.55) FOLH1CPB1CPB2HTTANPEP
SCHEMBL16575040 0.80 HTT (0.55) FOLH1CPB1CPB2HTTANPEP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240207355-A1 PHARMACEUTICAL COMPOSITION FOR ENHANCING ANTICANCER EFFECT OF ANTICANCER DRUG L-Base Co., Ltd. (KR) 2024-06-27 US disclosed
US-20230159587-A1 PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING CANCER L-Base Co., Ltd. (KR) 2023-05-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230159587-A1 PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING CANCER VIP, QPCT, TPT1 FOLH1 193/4885CPB1 894/4885CPB2 1448/4885
US-20240207355-A1 PHARMACEUTICAL COMPOSITION FOR ENHANCING ANTICANCER EFFECT OF ANTICANCER DRUG ALPG, SLC11A2, SGTA FOLH1 133/4885CPB1 2332/4885CPB2 3366/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.