SCHEMBL9604544

SCHEMBL9604544

C[C@@H](CCCCNC(=O)OCc1ccccc1)C(=O)O

nearest known ligand 0.66

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 5/20 0.62
HTT P42858 1/20 0.62
TGM2 P21980 1/20 0.59
MMP2 P08253 1/20 0.58
MMP9 P14780 1/20 0.58
LMNA P02545 1/20 0.57
SMN1; SMN2 Q16637 1/20 0.57
CPB1 P15086 1/20 0.57
CPB2 Q96IY4 1/20 0.57
DPP8 Q6V1X1 1/20 0.57
DPP7 Q9UHL4 1/20 0.57
KEAP1 Q14145 1/20 0.56
NFE2L2 Q16236 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17250893 1.00 FOLH1 (0.62) FOLH1HTTTGM2MMP2MMP9
SCHEMBL13471242 1.00 FOLH1 (0.62) FOLH1HTTTGM2MMP2MMP9
SCHEMBL8437001 0.96 HTT (0.63) FOLH1HTTTGM2MMP2MMP9
SCHEMBL18020349 0.96 HTT (0.63) FOLH1HTTTGM2MMP2MMP9
SCHEMBL15697210 0.96 HTT (0.63) FOLH1HTTTGM2MMP2MMP9
SCHEMBL16575045 0.95 CPB1 (0.58) FOLH1HTTTGM2MMP2MMP9
SCHEMBL14806727 0.91 HTT (0.60) FOLH1HTTTGM2MMP2MMP9
SCHEMBL16269912 0.90 SLC1A3 (0.62) FOLH1HTTTGM2LMNASMN1; SMN2
SCHEMBL18085402 0.90 SLC1A3 (0.62) FOLH1HTTTGM2LMNASMN1; SMN2
SCHEMBL14194799 0.90 HTT (0.59) FOLH1HTTTGM2MMP2MMP9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240226343-A1 NEUROPEPTIDE Y1 RECEPTOR (NPY1R) TARGETED THERAPEUTICS AND USES THEREOF RADIONETICS ONCOLOGY, INC. 2024-07-11 US disclosed
US-20240207292-A1 BORONIC ACID COMPOUNDS, COMPOSITIONS AND METHODS TRUSTEES OF TUFTS COLLEGE 2024-06-27 US disclosed
US-20240207355-A1 PHARMACEUTICAL COMPOSITION FOR ENHANCING ANTICANCER EFFECT OF ANTICANCER DRUG L-Base Co., Ltd. (KR) 2024-06-27 US disclosed
US-20230330275-A1 FAP-TARGETED RADIOPHARMACEUTICALS AND IMAGING AGENTS, AND USES RELATED THERETO TRUSTEES OF TUFTS COLLEGE 2023-10-19 US disclosed
US-20230310435-A1 HOST DEFENSE PROTEIN (HDP) MIMETICS FOR PROPHYLAXIS AND/OR TREATMENT OF INFLAMMATORY DISEASES OF THE GASTROINTESTINAL TRACT INNOVATION PHARMACEUTICALS INC. (US) 2023-10-05 US disclosed
US-11707539-B2 FAP-targeted radiopharmaceuticals and imaging agents, and uses related thereto TRUSTEES OF TUFTS COLLEGE (US) 2023-07-25 US disclosed
US-11666653-B2 Carbohydrate conjugates as delivery agents for oligonucleotides ALNYLAM PHARMACEUTICALS, INC. (US) 2023-06-06 US disclosed
US-11666571-B2 Host defense protein (HDP) mimetics for prophylaxis and/or treatment of inflammatory diseases of the gastrointestinal tract INNOVATION PHARMACEUTICALS INC. (US) 2023-06-06 US disclosed
US-20230159587-A1 PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING CANCER L-Base Co., Ltd. (KR) 2023-05-25 US disclosed
US-9988375-B2 Inhibitors of lysine gingipain Cortexyme, Inc. (US) 2018-06-05 US disclosed
US-8828956-B2 Carbohydrate conjugates as delivery agents for oligonucleotides ALNYLAM PHARMACEUTICALS, INC. (US) 2014-09-09 US disclosed
US-20140179761-A1 TARGETING LIPIDS TEKMIRA PHARMACEUTICALS CORPORATION (CA) 2014-06-26 US disclosed
US-20140148500-A1 PROGRAMMABLE SELF-ASSEMBLED NANOSTRUCTURES BASED ON SIDECHAIN-MODIFIED PNA FOR THE MULTIVALENT DISPLAY OF LIGANDS THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES 2014-05-29 US disclosed
US-20130274502-A1 Processes For Preparing A Polymeric Compound POLYMEDIX, INC. (US) 2013-10-17 US disclosed
US-20130178512-A1 CARBOHYDRATE CONJUGATES AS DELIVERY AGENTS FOR OLIGONUCLEOTIDES ALNYLAM PHARMACEUTICALS, INC (US) 2013-07-11 US disclosed
US-8450467-B2 Carbohydrate conjugates as delivery agents for oligonucleotides ALNYLAM PHARMACEUTICALS, INC. (US) 2013-05-28 US disclosed
US-20130078671-A1 INCORPORATION OF TWO DIFFERENT NONCANONICAL AMINO ACIDS INTO A SINGLE PROTEIN THE TEXAS A&M UNIVERSITY SYSTEM (US) 2013-03-28 US disclosed
US-8354556-B2 Processes for preparing a polymeric compound POLYMEDIX, INC. (US) 2013-01-15 US disclosed
US-20120136042-A1 CARBOHYDRATE CONJUGATES AS DELIVERY AGENTS FOR OLIGONUCLEOTIDES ALNYLAM PHARMACEUTICALS, INC (US) 2012-05-31 US disclosed
US-20110098498-A1 Processes For Preparing A Polymeric Compound POLYMEDIX, INC. (US) 2011-04-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (16 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110098498-A1 Processes For Preparing A Polymeric Compound F12, ALG1, ABCB11 FOLH1 819/4885HTT 2013/4885TGM2 4227/4885
US-20230159587-A1 PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING CANCER VIP, QPCT, TPT1 FOLH1 193/4885HTT 896/4885TGM2 1240/4885
US-20230330275-A1 FAP-TARGETED RADIOPHARMACEUTICALS AND IMAGING AGENTS, AND USES RELATED THERETO FAP, APC, FIBP FOLH1 19/4885HTT 2824/4885TGM2 567/4885
US-20130178512-A1 CARBOHYDRATE CONJUGATES AS DELIVERY AGENTS FOR OLIGONUCLEOTIDES LPXN, ZYX, OSTC FOLH1 1753/4885HTT 4363/4885TGM2 2566/4885
US-11666571-B2 Host defense protein (HDP) mimetics for prophylaxis and/or treatment of inflammatory diseases of the gastrointestinal tract FABP2, HMGB1, MASP2 FOLH1 1646/4885HTT 1086/4885TGM2 448/4885
US-20140179761-A1 TARGETING LIPIDS LY96, ABHD10, APOB FOLH1 695/4885HTT 1580/4885TGM2 2525/4885
US-20140148500-A1 PROGRAMMABLE SELF-ASSEMBLED NANOSTRUCTURES BASED ON SIDECHAIN-MODIFIED PNA FOR THE MULTIVALENT DISPLAY OF LIGANDS NCL, PARN, COIL FOLH1 3466/4885HTT 1367/4885TGM2 2657/4885
US-11707539-B2 FAP-targeted radiopharmaceuticals and imaging agents, and uses related thereto FAP, APC, FIBP FOLH1 19/4885HTT 2824/4885TGM2 567/4885
US-11666653-B2 Carbohydrate conjugates as delivery agents for oligonucleotides HAVCR2, B3GAT3, CSGALNACT1 FOLH1 253/4885HTT 2961/4885TGM2 2023/4885
US-20240207355-A1 PHARMACEUTICAL COMPOSITION FOR ENHANCING ANTICANCER EFFECT OF ANTICANCER DRUG ALPG, SLC11A2, SGTA FOLH1 133/4885HTT 1250/4885TGM2 847/4885
US-20130078671-A1 INCORPORATION OF TWO DIFFERENT NONCANONICAL AMINO ACIDS INTO A SINGLE PROTEIN AARS1, NSUN3, NPEPPS FOLH1 794/4885HTT 1020/4885TGM2 901/4885
US-20240207292-A1 BORONIC ACID COMPOUNDS, COMPOSITIONS AND METHODS BCL6B, BCL6, BTD FOLH1 2860/4885HTT 627/4885TGM2 3516/4885
US-20120136042-A1 CARBOHYDRATE CONJUGATES AS DELIVERY AGENTS FOR OLIGONUCLEOTIDES LPXN, ZYX, OSTC FOLH1 1753/4885HTT 4363/4885TGM2 2566/4885
US-20240226343-A1 NEUROPEPTIDE Y1 RECEPTOR (NPY1R) TARGETED THERAPEUTICS AND USES THEREOF NPY1R, NPY2R, NPY4R FOLH1 335/4885HTT 1975/4885TGM2 3235/4885
US-20230310435-A1 HOST DEFENSE PROTEIN (HDP) MIMETICS FOR PROPHYLAXIS AND/OR TREATMENT OF INFLAMMATORY DISEASES OF THE GASTROINTESTINAL TRACT FABP2, HMGB1, MASP2 FOLH1 1646/4885HTT 1086/4885TGM2 448/4885
US-20130274502-A1 Processes For Preparing A Polymeric Compound F12, ALG1, ABCB11 FOLH1 819/4885HTT 2013/4885TGM2 4227/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.