SCHEMBL2555255

SCHEMBL2555255

BrCc1ccccc1Br.c1ccc(P(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
TAAR1 Q96RJ0 3/20 0.42
IDO1 P14902 2/20 0.41
ESR1 P03372 2/20 0.40
ESR2 Q92731 2/20 0.40
TSHR P16473 3/20 0.39
CYP1A2 P05177 1/20 0.36
CYP2D6 P10635 1/20 0.36
NFKB1 P19838 1/20 0.36
CYP2C19 P33261 1/20 0.36
HSD17B10 Q99714 1/20 0.36
ALDH1A1 P00352 2/20 0.36
TRPA1 O75762 1/20 0.36
LMNA P02545 1/20 0.35
BLM P54132 1/20 0.35
CYP2A13 Q16696 1/20 0.34
KDM1A O60341 1/20 0.34
FFAR1 O14842 1/20 0.34
FFAR4 Q5NUL3 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL217088 0.84
Bromide SCHEMBL28890803 0.82 TAAR1 (0.52) TAAR1IDO1TSHRCYP1A2CYP2D6
SCHEMBL2907749 0.82 TAAR1 (0.52) TAAR1IDO1TSHRCYP1A2CYP2D6
SCHEMBL16393596 0.82 TAAR1 (0.52) TAAR1IDO1TSHRCYP1A2CYP2D6
SCHEMBL21931634 0.78 ESR1 (0.48) CYP3A4TDP1TAAR1IDO1ESR1
SCHEMBL7364761 0.78 CYP3A4 (0.48) CYP3A4TDP1TAAR1IDO1ESR1
SCHEMBL2647307 0.78 CYP3A4 (0.48) CYP3A4TDP1TAAR1ESR1ESR2
SCHEMBL10966676 0.77 CYP3A4 (0.43) CYP3A4TDP1TAAR1IDO1ESR1
SCHEMBL4898935 0.77 TDP1 (0.46) CYP3A4TDP1ESR1ESR2TSHR
Dibromomethane SCHEMBL5329477 0.77 TDP1 (0.75) CYP3A4TDP1IDO1ESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118239985-A Organic electroluminescent material and device 环球展览公司 2024-06-25 CN disclosed
CN-116323557-A Cyclobutylamide monoacylglycerol lipase modulators 詹森药业有限公司 2023-06-23 CN disclosed
US-20130059996-A1 Boron-Containing PI-Electron Materials Incorporating Formally Aromatic and Neutral Borepin Rings THE JOHNS HOPKINS UNIVERSITY 2013-03-07 US disclosed
WO-2011127383-A2 BORON-CONTAINING PI-ELECTRON MATERIALS INCORPORATING FORMALLY AROMATIC AND NEUTRAL BOREPIN RINGS THE JOHNS HOPKINS UNIVERSITY (US) 2011-10-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130059996-A1 Boron-Containing PI-Electron Materials Incorporating Formally Aromatic and Neutral Borepin Rings PNN, CIAPIN1, VNN1 CYP3A4 1131/4885TDP1 1488/4885TAAR1 77/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.