SCHEMBL2555302

SCHEMBL2555302

Cc1c(B(O)O)ccc(O[Si](C)(C)C(C)(C)C)c1O[Si](C)(C)C(C)(C)C

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 1/20 0.33
ALOX5AP P20292 1/20 0.30
FEN1 P39748 1/20 0.30
PREP P48147 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2913405 0.79 ENPP2 (0.39) DRD2PREP
SCHEMBL3440600 0.75 ALOX5AP (0.33) DRD2ALOX5APFEN1
SCHEMBL15912872 0.74 ALOX5AP (0.38) ALOX5APFEN1PREP
SCHEMBL25400416 0.74 DRD2 (0.33) DRD2PREP
SCHEMBL30618374 0.74 DRD2 (0.33) DRD2PREP
SCHEMBL15269311 0.73 ENPP2 (0.52) DRD2
SCHEMBL20582850 0.73 DRD2 (0.35) DRD2ALOX5APFEN1PREP
SCHEMBL6112114 0.71 DRD2 (0.40) DRD2
SCHEMBL2367203 0.71 CA12 (0.34) DRD2PREP
SCHEMBL19975327 0.70 PREP (0.35) ALOX5APFEN1PREP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11225655-B2 Bi-functional complexes and methods for making and using such complexes NUEVOLUTION A/S (DK) 2022-01-18 US disclosed
EP-3540059-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES Nuevolution A/S (DK) 2019-09-18 EP disclosed
EP-2558577-B1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION AS (DK) 2018-12-12 EP disclosed
US-20130281324-A1 BI-FUNCTINAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2013-10-24 US disclosed
EP-2558577-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES Nuevolution A/S (DK) 2013-02-20 EP disclosed
WO-2011127933-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2011-10-20 WO disclosed