Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 7/20 | 0.56 |
| ▸ | TAAR1 | Q96RJ0 | 5/20 | 0.56 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.56 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.56 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.56 |
| ▸ | MAOA | P21397 | 1/20 | 0.56 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.56 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.56 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.56 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.50 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.48 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.47 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13006663 | 1.00 | SIGMAR1 (0.56) | SIGMAR1TAAR1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL13189946 | 1.00 | SIGMAR1 (0.56) | SIGMAR1TAAR1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL43314 | 0.90 | SLC6A4 (0.46) | SIGMAR1TAAR1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL44955 | 0.86 | TAAR1 (0.50) | SIGMAR1TAAR1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL9418953 | 0.85 | SIGMAR1 (0.47) | SIGMAR1TAAR1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL14764261 | 0.82 | TAAR1 (0.52) | SIGMAR1TAAR1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL112281 | 0.82 | TAAR1 (0.52) | SIGMAR1TAAR1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL1256615 | 0.82 | SIGMAR1 (0.58) | SIGMAR1TAAR1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL412663 | 0.82 | SIGMAR1 (0.58) | SIGMAR1TAAR1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6551869 | 0.81 | AGXT (0.41) | TAAR1SLC6A4CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 75 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111171197-B | Method for preparing high-activity polyisobutylene by using bifunctional initiator and application | 北京石油化工学院 | 2022-08-02 | — | — | CN | claimed |
| CN-111171197-A | Method for preparing high-activity polyisobutylene by using bifunctional initiator and application | 北京石油化工学院 | 2020-05-19 | — | — | CN | claimed |
| CN-111094394-A | Polyolefin dispersants and methods of making and using the same | 雪佛龙奥伦耐有限责任公司 | 2020-05-01 | — | — | CN | claimed |
| EP-1979362-B1 | NOVEL SILANE COMPOUNDS AND USE THEREOF IN ORDER TO FUNCTIONALISE SOLID MEDIA AND IMMOBILISE BIOLOGICAL MOLECULES ON SAID MEDIA | COMMISSARIAT ENERGIE ATOMIQUE (FR) | 2010-12-15 | — | — | EP | claimed |
| WO-2010131145-A1 | CYCLOBUTENEDIONE DERIVATIVES | PFIZER LIMITED (GB) | 2010-11-18 | — | — | WO | claimed |
| WO-2010131147-A1 | CYCLOBUTENEDIONE DERIVATIVES | PFIZER LIMITED (GB) | 2010-11-18 | — | — | WO | claimed |
| WO-2010131146-A1 | CYCLOBUTENEDIONE DERIVATIVES | PFIZER LIMITED (GB) | 2010-11-18 | — | — | WO | claimed |
| EP-3262036-B1 | THERAPEUTIC PYRIDAZINE COMPOUNDS AND USES THEREOF | GENENTECH INC (US) | 2023-09-13 | — | — | EP | disclosed |
| CN-116514679-A | Palladium-catalyzed sp with low-cost and high-efficiency quaternary ammonium nitrate as oxidant 2 And sp (sp) 3 Carbon hydrogen bond alkenylation method | 南京工业大学 | 2023-08-01 | — | — | CN | disclosed |
| CN-111253583-B | Dilatant hybrid dynamic polymer and dilatant realization method thereof | 厦门天策材料科技有限公司 | 2023-05-16 | — | — | CN | disclosed |
| CN-111171197-B | Method for preparing high-activity polyisobutylene by using bifunctional initiator and application | 北京石油化工学院 | 2022-08-02 | — | — | CN | disclosed |
| US-10889146-B2 | Tire object provided with an elastomer layer made of a thermoplastic elastomer in the form of an (A-b-(a-methylstyrene-co-B))n-b-C block copolymer | COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) | 2021-01-12 | — | — | US | disclosed |
| CN-111378176-A | Energy absorption method based on force-induced responsive cross-linked polymer with multiple networks | 翁秋梅 | 2020-07-07 | — | — | CN | disclosed |
| WO-1996006118-A1 | CATIONIC POLYMERIZATION IN CARBON DIOXIDE | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 1996-02-29 | — | — | WO | disclosed |
| EP-0659747-A1 | Branched aminothiazole derivatives process for their preparation and pharmaceutical compositions containing them | SANOFI (FR) | 1995-06-28 | — | — | EP | disclosed |
| US-4985442-A | ANTIINFLAMMATORY, LUNG DISEASES, PSORIASIS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-01-15 | — | — | US | disclosed |
| WO-1990010657-A1 | POLYURETHANE FOAM | THE UNIVERSITY OF AKRON (US) | 1990-09-20 | — | — | WO | disclosed |
| US-4939184-A | DIOL IS HYDROXY ENDCAPPED POLYISOBUTYLENE | UNIVERSITY OF AKRON (US) | 1990-07-03 | — | — | US | disclosed |
| US-4383090-A | HIGH SPEED; COCURING AGENT OF POLYAMIDE-POLYLACTAM COPOLYMER; FILMS; CASTINGS; POTTING; ADHESIVES | DIAMOND SHAMROCK CORPORATION (US) | 1983-05-10 | — | — | US | disclosed |
| EP-0075827-A2 | Polyepoxide curing by polymercaptans plus catalytic co-curing agents | DIAMOND SHAMROCK CHEMICALS COMPANY (US) | 1983-04-06 | — | — | EP | disclosed |