Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LGMN | Q99538 | 1/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | MET | P08581 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.34 |
| ▸ | F12 | P00748 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | SMO | Q99835 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | MTOR | P42345 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25168606 | 0.93 | LGMN (0.38) | LGMNPDE10AALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL25195166 | 0.88 | PDE10A (0.35) | LGMNPDE10AALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL25448035 | 0.88 | MAPT (0.36) | PDE10AALDH1A1MAPTHRH3MET | |
| SCHEMBL25168645 | 0.87 | LGMN (0.45) | LGMNPDE10AALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL30407686 | 0.87 | LGMN (0.45) | LGMNPDE10AALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL25554103 | 0.84 | CASP6 (0.43) | MAPTNPC1RAB9AMEN1KMT2A | |
| SCHEMBL25171946 | 0.84 | MAPT (0.39) | LGMNALDH1A1SMN1; SMN2MAPTNPC1 | |
| SCHEMBL25174602 | 0.83 | KDM4E (0.38) | LGMNPDE10AALDH1A1HRH3MET | |
| SCHEMBL25194368 | 0.81 | MAP4K4 (0.32) | PDE10AALDH1A1MAPTHRH3RAB9A | |
| SCHEMBL30407535 | 0.81 | MAP4K4 (0.32) | PDE10AALDH1A1MAPTHRH3RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023081666-A1 | COMPOUNDS AS CCR2 MODULATORS | ARIA PHARMACEUTICALS, INC. (US) | 2023-05-11 | — | — | WO | disclosed |