Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LGMN | Q99538 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25168645 | 1.00 | LGMN (0.45) | LGMNPOLBPDE10AAKR1C3MAPT | |
| SCHEMBL25554102 | 0.87 | LGMN (0.38) | LGMNPOLBPDE10AAKR1C3MAPT | |
| SCHEMBL25168606 | 0.87 | LGMN (0.38) | LGMNPOLBPDE10AAKR1C3MAPT | |
| SCHEMBL25448035 | 0.87 | MAPT (0.36) | PDE10AMAPTALDH1A1KDM4EMEN1 | |
| SCHEMBL25171946 | 0.86 | MAPT (0.39) | LGMNMAPTALDH1A1SMN1; SMN2RAB9A | |
| SCHEMBL25174602 | 0.85 | KDM4E (0.38) | LGMNPOLBPDE10AAKR1C3ALDH1A1 | |
| SCHEMBL25554103 | 0.84 | CASP6 (0.43) | AKR1C3MAPTMEN1KMT2ARAB9A | |
| SCHEMBL25195166 | 0.83 | PDE10A (0.35) | LGMNPDE10AMAPTALDH1A1MEN1 | |
| SCHEMBL25184666 | 0.82 | CDK4 (0.34) | LGMNMAPTKDM4E | |
| SCHEMBL30406704 | 0.82 | CDK4 (0.34) | LGMNMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023081666-A1 | COMPOUNDS AS CCR2 MODULATORS | ARIA PHARMACEUTICALS, INC. (US) | 2023-05-11 | — | — | WO | disclosed |