Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP6 | P55212 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | AOC3 | Q16853 | 11/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.39 |
| ▸ | WNT3A | P56704 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25448035 | 0.87 | MAPT (0.36) | GFERMEN1MAPTKMT2A | |
| SCHEMBL25554102 | 0.84 | LGMN (0.38) | AKR1C3MEN1MAPTKMT2ANPC1 | |
| SCHEMBL25168606 | 0.84 | LGMN (0.38) | AOC3AKR1C3MEN1MAPTKMT2A | |
| SCHEMBL30407686 | 0.84 | LGMN (0.45) | AKR1C3MEN1MAPTKMT2ANPC1 | |
| SCHEMBL25168645 | 0.84 | LGMN (0.45) | AKR1C3MEN1MAPTKMT2ANPC1 | |
| SCHEMBL25174602 | 0.82 | KDM4E (0.38) | AKR1C3WNT3A | |
| SCHEMBL25171946 | 0.81 | MAPT (0.39) | MAPTNPC1RAB9A | |
| SCHEMBL25448070 | 0.81 | OPRM1 (0.38) | AOC3MEN1KMT2A | |
| SCHEMBL25184671 | 0.81 | PDK2 (0.41) | MAPTNPC1RAB9A | |
| SCHEMBL25195166 | 0.80 | PDE10A (0.35) | MEN1MAPTKMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023081666-A1 | COMPOUNDS AS CCR2 MODULATORS | ARIA PHARMACEUTICALS, INC. (US) | 2023-05-11 | — | — | WO | disclosed |