Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 1/20 | 0.60 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.53 |
| ▸ | FNTA | P49354 | 1/20 | 0.47 |
| ▸ | FNTB | P49356 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MRGPRX4 | Q96LA9 | 4/20 | 0.46 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.45 |
| ▸ | PTGER1 | P34995 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15330173 | 0.87 | ENPP2 (0.57) | MAPTSMN1; SMN2NPC1RAB9AENPP2 | |
| SCHEMBL2554921 | 0.83 | TP53 (0.46) | MAPTSMN1; SMN2NPC1RAB9AENPP2 | |
| SCHEMBL29952431 | 0.80 | ENPP2 (0.66) | MAPTSMN1; SMN2NPC1RAB9AENPP2 | |
| SCHEMBL8453 | 0.80 | ENPP2 (0.66) | MAPTSMN1; SMN2NPC1RAB9AENPP2 | |
| SCHEMBL3319862 | 0.78 | MAPT (0.60) | MAPTSMN1; SMN2NPC1RAB9AFNTA | |
| SCHEMBL17858627 | 0.78 | MAPT (0.60) | MAPTSMN1; SMN2NPC1RAB9AFNTA | |
| SCHEMBL15332082 | 0.78 | LMNA (0.43) | MAPTSMN1; SMN2NPC1RAB9APKM | |
| SCHEMBL12260343 | 0.77 | ENPP2 (0.63) | SMN1; SMN2NPC1RAB9AENPP2MRGPRX4 | |
| SCHEMBL3761511 | 0.76 | MAOB (0.59) | SMN1; SMN2NPC1RAB9APKMTDP1 | |
| SCHEMBL19736986 | 0.76 | RAB9A (0.57) | MAPTSMN1; SMN2NPC1RAB9AFNTA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| US-11225655-B2 | Bi-functional complexes and methods for making and using such complexes | NUEVOLUTION A/S (DK) | 2022-01-18 | — | — | US | disclosed |
| CN-108368107-B | Fused heterocyclic compounds as S1P modulators | 艾伯维公司 | 2021-11-26 | — | — | CN | disclosed |
| US-10556907-B2 | Fused heterocyclic compounds as S1P modulators | AbbVie Deutschland GmbH & Co. KG (DE) | 2020-02-11 | — | — | US | disclosed |
| US-20190327974-A1 | SYNERGISTS FOR IMPROVED PESTICIDES | THE AUSTRALIAN NATIONAL UNIVERSITY (AU) | 2019-10-31 | — | — | US | disclosed |
| US-20190327974-A1 | SYNERGISTS FOR IMPROVED PESTICIDES | THE AUSTRALIAN NATIONAL UNIVERSITY (AU) | 2019-10-31 | — | — | US | disclosed |
| EP-3540059-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | Nuevolution A/S (DK) | 2019-09-18 | — | — | EP | disclosed |
| EP-2558577-B1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION AS (DK) | 2018-12-12 | — | — | EP | disclosed |
| WO-2018127928-A1 | SYNERGISTS FOR IMPROVED PESTICIDES | THE AUSTRALIAN NATIONAL UNIVERSITY (AU) | 2018-07-12 | — | — | WO | disclosed |
| WO-2018127928-A1 | SYNERGISTS FOR IMPROVED PESTICIDES | THE AUSTRALIAN NATIONAL UNIVERSITY (AU) | 2018-07-12 | — | — | WO | disclosed |
| US-20170057966-A1 | FUSED HETEROCYCLIC COMPOUNDS AS S1P MODULATORS | AbbVie Deutschland GmbH & Co. KG (DE) | 2017-03-02 | — | — | US | disclosed |
| US-20130281324-A1 | BI-FUNCTINAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2013-10-24 | — | — | US | disclosed |
| EP-2558577-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | Nuevolution A/S (DK) | 2013-02-20 | — | — | EP | disclosed |
| WO-2011127933-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2011-10-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190327974-A1 | SYNERGISTS FOR IMPROVED PESTICIDES | BCHE, DDT, DBF4 | MAPT 2085/4885SMN1; SMN2 1786/4885NPC1 2275/4885 |
| US-20170057966-A1 | FUSED HETEROCYCLIC COMPOUNDS AS S1P MODULATORS | S1PR1, S1PR2, S1PR3 | MAPT 3696/4885SMN1; SMN2 3709/4885NPC1 167/4885 |
| US-10556907-B2 | Fused heterocyclic compounds as S1P modulators | S1PR1, S1PR2, S1PR3 | MAPT 3696/4885SMN1; SMN2 3709/4885NPC1 167/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.