Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | THRB | P10828 | 1/20 | 0.57 |
| ▸ | BLM | P54132 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | TRIM24 | O15164 | 2/20 | 0.46 |
| ▸ | TRIM33 | Q9UPN9 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ERN1 | O75460 | 2/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 4/20 | 0.36 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28928203 | 0.93 | LMNA (0.50) | LMNAKMT2AMEN1THRBBLM | |
| SCHEMBL29197892 | 0.79 | KMT2A (0.44) | LMNAKMT2AMEN1THRBBLM | |
| SCHEMBL28958589 | 0.78 | ALDH1A1 (0.44) | LMNAKMT2AMEN1THRBBLM | |
| SCHEMBL7245064 | 0.74 | MEN1 (0.32) | LMNAKMT2AMEN1THRBBLM | |
| Ortho-Phthalaldehyde SCHEMBL33393 | 0.74 | LMNA (1.00) | LMNAKMT2AMEN1THRBBLM | |
| Ortho-Phthalaldehyde SCHEMBL4953869 | 0.74 | LMNA (1.00) | LMNAKMT2AMEN1THRBBLM | |
| Ortho-Phthalaldehyde SCHEMBL29412642 | 0.74 | LMNA (1.00) | LMNAKMT2AMEN1THRBBLM | |
| SCHEMBL28465753 | 0.73 | NFE2L2 (0.50) | LMNAKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| Ortho-Phthalaldehyde SCHEMBL10792496 | 0.72 | LMNA (0.93) | LMNAKMT2AMEN1THRBBLM | |
| Ortho-Phthalaldehyde SCHEMBL6688449 | 0.72 | LMNA (0.93) | LMNAKMT2AMEN1THRBBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230151035-A1 | Preparation method for and application of chiral spirocyclic phosphine-nitrogen-phosphine tridentate ligand and iridium catalyst thereof | ZHEJIANG JIUZHOU PHARM CO LTD (CN) | 2023-05-18 | — | — | US | disclosed |
| CN-108003309-A | A kind of phenolic resin curing agent and preparation method thereof | 嘉兴市东方化工厂 | 2018-05-08 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230151035-A1 | Preparation method for and application of chiral spirocyclic phosphine-nitrogen-phosphine tridentate ligand and iridium catalyst thereof | SPR, PKD1, ROR1 | LMNA 4595/4885KMT2A 3210/4885MEN1 1762/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.