Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.31 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.31 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | DRD3 | P35462 | 1/20 | 0.30 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.30 |
| ▸ | KDM1A | O60341 | 1/20 | 0.30 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22253854 | 1.00 | HRH3 (0.33) | HRH3PARP1CYP2D6KCNH2GNAI3 | |
| SCHEMBL12209129 | 1.00 | HRH3 (0.33) | HRH3PARP1CYP2D6KCNH2GNAI3 | |
| SCHEMBL22752741 | 0.93 | HRH3 (0.34) | HRH3CYP2D6KCNH2 | |
| SCHEMBL22314113 | 0.93 | HRH3 (0.34) | HRH3CYP2D6KCNH2 | |
| SCHEMBL222544 | 0.91 | CHRNA7 (0.34) | HRH3CYP2D6KCNH2GNAI3GNAO1 | |
| Hydrochloric Acid SCHEMBL222616 | 0.88 | GNAI3 (0.38) | HRH3CYP2D6KCNH2GNAI3GNAO1 | |
| Hydrochloric Acid SCHEMBL1456033 | 0.88 | GNAI3 (0.38) | HRH3CYP2D6KCNH2GNAI3GNAO1 | |
| Hydrochloric Acid SCHEMBL3410008 | 0.86 | HRH3 (0.33) | HRH3CYP2D6KCNH2GNAI3GNAO1 | |
| SCHEMBL2424015 | 0.82 | DRD2 (0.36) | PARP1KCNH2DRD2DRD3KDM2B | |
| SCHEMBL2424503 | 0.82 | DRD2 (0.36) | PARP1KCNH2DRD2DRD3KDM2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230159491-A1 | Antimicrobial Compounds and Methods | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2023-05-25 | — | — | US | disclosed |
| WO-2023083269-A1 | AROMATIC HETEROCYCLIC COMPOUND AND APPLICATION THEREOF | 中国科学院上海药物研究所 | 2023-05-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230159491-A1 | Antimicrobial Compounds and Methods | MPO, NISCH, RPN2 | HRH3 2165/4885PARP1 468/4885CYP2D6 1521/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.