Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2421484 | 0.91 | ALDH1A1 (0.42) | ALDH1A1HSD17B10THRBATML3MBTL1 | |
| SCHEMBL2422221 | 0.91 | ALDH1A1 (0.48) | ALDH1A1HSD17B10THRBATML3MBTL1 | |
| SCHEMBL25069386 | 0.91 | ALDH1A1 (0.33) | ALDH1A1HSD17B10THRBATML3MBTL1 | |
| SCHEMBL20235023 | 0.89 | ALDH1A1 (0.35) | ALDH1A1HSD17B10THRBATML3MBTL1 | |
| SCHEMBL25069568 | 0.86 | ALDH1A1 (0.37) | ALDH1A1HSD17B10THRBATML3MBTL1 | |
| SCHEMBL25538020 | 0.83 | KDM1A (0.30) | — | |
| SCHEMBL24091124 | 0.83 | SIGMAR1 (0.30) | SIGMAR1 | |
| SCHEMBL25538013 | 0.83 | SIGMAR1 (0.30) | SIGMAR1 | |
| SCHEMBL8260651 | 0.82 | ALDH1A1 (0.42) | ALDH1A1HSD17B10THRBATML3MBTL1 | |
| SCHEMBL21004528 | 0.82 | ALDH1A1 (0.42) | ALDH1A1HSD17B10THRBATML3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230159491-A1 | Antimicrobial Compounds and Methods | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2023-05-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230159491-A1 | Antimicrobial Compounds and Methods | MPO, NISCH, RPN2 | ALDH1A1 3752/4885HSD17B10 3006/4885THRB 4623/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.