Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT6A | Q92794 | 4/20 | 0.38 |
| ▸ | KAT7 | O95251 | 3/20 | 0.38 |
| ▸ | KAT6B | Q8WYB5 | 2/20 | 0.38 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | IP6K1 | Q92551 | 2/20 | 0.34 |
| ▸ | IP6K3 | Q96PC2 | 2/20 | 0.34 |
| ▸ | IP6K2 | Q9UHH9 | 2/20 | 0.34 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31432518 | 1.00 | KAT6A (0.38) | KAT6AKAT7KAT6BMAP4K4PTGS2 | |
| SCHEMBL25561707 | 0.78 | KAT6A (0.67) | KAT6AKAT7KAT6B | |
| SCHEMBL30360820 | 0.78 | KAT6A (0.67) | KAT6AKAT7KAT6B | |
| SCHEMBL29652491 | 0.78 | NPC1 (0.48) | KAT6AKAT7KAT6BNPC1ALDH1A1 | |
| SCHEMBL21596901 | 0.78 | NPC1 (0.48) | KAT6AKAT7KAT6BNPC1ALDH1A1 | |
| SCHEMBL25564467 | 0.77 | KAT6A (0.42) | KAT6AKAT7KAT6B | |
| SCHEMBL25566016 | 0.76 | HCRTR1 (0.32) | KAT6AKAT7KAT6BALDH1A1KDM4E | |
| SCHEMBL4796565 | 0.73 | ALDH1A1 (0.53) | MAP4K4PTGS2ALDH1A1KDM4EMEN1 | |
| SCHEMBL21596793 | 0.72 | FYN (0.44) | MAP4K4NPC1ALDH1A1MAPTKDM4E | |
| SCHEMBL21596846 | 0.71 | LTB4R (0.34) | KAT6AKAT7KAT6BMAP4K4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023088233-A1 | LYSINE ACETYLTRANSFERASE 6A (KAT6A) INHIBITORS AND USES THEREOF | INSILICO MEDICINE IP LIMITED (CN) | 2023-05-25 | — | — | WO | disclosed |