Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.39 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.39 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | TGM2 | P21980 | 1/20 | 0.36 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.36 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.35 |
| ▸ | NMT1 | P30419 | 4/20 | 0.34 |
| ▸ | NMT2 | O60551 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21206343 | 0.86 | SIRT1 (0.40) | SIRT6SIRT1GRIA1POLBTGM2 | |
| SCHEMBL28670837 | 0.83 | FOLH1 (0.50) | POLBTGM2FOLH1SMN1; SMN2 | |
| SCHEMBL28670835 | 0.83 | FOLH1 (0.50) | POLBTGM2FOLH1SMN1; SMN2 | |
| SCHEMBL13671361 | 0.83 | POLB (0.41) | SIRT6SIRT1GRIA1EPHX1POLB | |
| SCHEMBL18630501 | 0.80 | POLB (0.41) | EPHX1POLBALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL23770334 | 0.77 | POLB (0.46) | EPHX1POLBALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL22727309 | 0.76 | SIRT6 (0.44) | SIRT6SIRT1EPHX1TGM2SIRT5 | |
| SCHEMBL22026768 | 0.76 | SIRT1 (0.41) | SIRT6SIRT1EPHX1SIRT5FOLH1 | |
| SCHEMBL26840286 | 0.76 | SIRT6 (0.44) | SIRT6SIRT1EPHX1TGM2SIRT5 | |
| SCHEMBL16283873 | 0.75 | NOD1 (0.47) | SIRT6SIRT1GRIA1POLBSIRT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230165882-A1 | COMPOUNDS AND METHODS FOR REDUCTION OF CANCER CELL BURDEN AND PROTECTION OF NORMAL HEMATOPOIESIS | GLYCOMIMETICS, INC. (US) | 2023-06-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230165882-A1 | COMPOUNDS AND METHODS FOR REDUCTION OF CANCER CELL BURDEN AND PROTECTION OF NORMAL HEMATOPOIESIS | FLT3, SELE, SELL | SIRT6 1190/4885SIRT1 533/4885GRIA1 2363/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.