Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 3/20 | 0.33 |
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | TTR | P02766 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7317772 | 0.72 | TRPA1 (0.41) | KCNN4ALDH1A1KIF11CYP2D6CYP2C19 | |
| SCHEMBL7312975 | 0.72 | TRPA1 (0.41) | KCNN4ALDH1A1KIF11CYP2D6CYP2C19 | |
| SCHEMBL7479981 | 0.70 | KCNN4 (0.43) | KCNN4ALDH1A1MEN1KMT2AKIF11 | |
| SCHEMBL7486375 | 0.69 | KCNN4 (0.44) | KCNN4ALDH1A1KIF11LMNACHRM3 | |
| SCHEMBL6566499 | 0.68 | KCNN4 (0.52) | KCNN4ALDH1A1MEN1KMT2AHTT | |
| SCHEMBL16609226 | 0.68 | KCNN4 (0.52) | KCNN4ALDH1A1MEN1KMT2AHTT | |
| SCHEMBL2490293 | 0.68 | KCNN4 (0.38) | KCNN4ALDH1A1MEN1KMT2AKIF11 | |
| SCHEMBL3302423 | 0.68 | KCNN4 (0.47) | KCNN4ALDH1A1MEN1KMT2AKIF11 | |
| SCHEMBL3302429 | 0.68 | KCNN4 (0.47) | KCNN4ALDH1A1MEN1KMT2AKIF11 | |
| SCHEMBL28513998 | 0.68 | KCNN4 (0.42) | KCNN4ALDH1A1MEN1KMT2AKIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110263607-A1 | ALPHA HELIX MIMETICS IN THE TREATMENT OF CANCER | PRISM BIOLAB CORPORATION (JP) | 2011-10-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110263607-A1 | ALPHA HELIX MIMETICS IN THE TREATMENT OF CANCER | COL1A1, HDGF, HCCS | KCNN4 4850/4885ALDH1A1 1264/4885MEN1 1160/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.