SCHEMBL25564927

SCHEMBL25564927

c1ccc(-c2ccc3c(c2)c2ccccc2n3-c2cc(-c3ccc([Si](c4ccccc4)(c4ccccc4)c4ccccc4)cc3)nc(-c3ccc([Si](c4ccccc4)(c4ccccc4)c4ccccc4)cc3)c2)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.39
L3MBTL1 Q9Y468 2/20 0.39
ATM Q13315 1/20 0.39
TSPO P30536 1/20 0.37
DHODH Q02127 1/20 0.35
NPY5R Q15761 2/20 0.35
PTGER4 P35408 1/20 0.33
PTGES O14684 1/20 0.33
ACHE P22303 1/20 0.33
TDP1 Q9NUW8 3/20 0.33
ALDH1A1 P00352 2/20 0.33
MAPT P10636 2/20 0.33
MAPK1 P28482 2/20 0.33
HPGD P15428 1/20 0.33
NR3C1 P04150 1/20 0.33
MEN1 O00255 1/20 0.33
NPC1 O15118 1/20 0.33
LMNA P02545 1/20 0.33
POLB P06746 1/20 0.33
GAA P10253 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25564932 0.93 KDM4E (0.36) KDM4EL3MBTL1ATMTSPODHODH
SCHEMBL25564930 0.93 KDM4E (0.37) KDM4EL3MBTL1ATMTSPODHODH
SCHEMBL24089290 0.92 KDM4E (0.46) KDM4EL3MBTL1ATMDHODHACHE
SCHEMBL10246666 0.91 L3MBTL1 (0.47) KDM4EL3MBTL1ATMTSPODHODH
SCHEMBL15449711 0.89 KDM4E (0.47) KDM4EL3MBTL1ATMTSPODHODH
SCHEMBL15748496 0.89 L3MBTL1 (0.51) KDM4EL3MBTL1ATMTSPODHODH
SCHEMBL18758302 0.89 KDM4E (0.46) KDM4EL3MBTL1ATMTSPONPY5R
SCHEMBL19653338 0.89 KMT2A (0.40) KDM4EL3MBTL1ATMTSPODHODH
SCHEMBL15449713 0.88 KDM4E (0.42) KDM4EL3MBTL1ATMTSPODHODH
SCHEMBL17206542 0.88 L3MBTL1 (0.49) KDM4EL3MBTL1ATMTSPONPY5R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240032415-A1 LIGHT-EMITTING DEVICE, ELECTRONIC APPARATUS INCLUDING THE SAME, AND ORGANOMETALLIC COMPOUND SAMSUNG DISPLAY CO., LTD. (KR) 2024-01-25 US disclosed
US-20240032415-A1 LIGHT-EMITTING DEVICE, ELECTRONIC APPARATUS INCLUDING THE SAME, AND ORGANOMETALLIC COMPOUND SAMSUNG DISPLAY CO., LTD. (KR) 2024-01-25 US disclosed
US-20230225188-A1 ORGANOMETALLIC COMPOUND, LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND ELECTRONIC APPARATUS INCLUDING THE LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2023-07-13 US disclosed
US-20230225188-A1 ORGANOMETALLIC COMPOUND, LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND ELECTRONIC APPARATUS INCLUDING THE LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2023-07-13 US disclosed
US-20230172053-A1 COMPOSITION, LIGHT-EMITTING DEVICE, ELECTRONIC APPARATUS, CONSUMER PRODUCT, AND ORGANOMETALLIC COMPOUND SAMSUNG DISPLAY CO., LTD. (KR) 2023-06-01 US disclosed
US-20230172053-A1 COMPOSITION, LIGHT-EMITTING DEVICE, ELECTRONIC APPARATUS, CONSUMER PRODUCT, AND ORGANOMETALLIC COMPOUND SAMSUNG DISPLAY CO., LTD. (KR) 2023-06-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230225188-A1 ORGANOMETALLIC COMPOUND, LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND ELECTRONIC APPARATUS INCLUDING THE LIGHT-EMITTING DEVICE GPX1, CRY1, LAGE3 KDM4E 1358/4885L3MBTL1 275/4885ATM 3402/4885
US-20240032415-A1 LIGHT-EMITTING DEVICE, ELECTRONIC APPARATUS INCLUDING THE SAME, AND ORGANOMETALLIC COMPOUND LAGE3, CRY1, LEF1 KDM4E 980/4885L3MBTL1 53/4885ATM 3575/4885
US-20230172053-A1 COMPOSITION, LIGHT-EMITTING DEVICE, ELECTRONIC APPARATUS, CONSUMER PRODUCT, AND ORGANOMETALLIC COMPOUND CYP1A1, CYP1B1, GPX1 KDM4E 2078/4885L3MBTL1 1048/4885ATM 3628/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.