Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.58 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.45 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 5/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | COMT | P21964 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.42 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25954435 | 0.97 | CLK4 (0.56) | CLK4ADRB2MEN1KMT2ATP53 | |
| SCHEMBL21018825 | 0.87 | CLK4 (0.47) | CLK4ADRB2MEN1KMT2ATP53 | |
| SCHEMBL27256810 | 0.86 | ALDH1A1 (0.47) | CLK4ADRB2MEN1KMT2ATP53 | |
| SCHEMBL17051406 | 0.86 | CLK4 (0.45) | CLK4ADRB2MEN1KMT2ATP53 | |
| SCHEMBL12628231 | 0.86 | MEN1 (0.50) | CLK4ADRB2MEN1KMT2ATP53 | |
| SCHEMBL6685962 | 0.86 | CLK4 (0.64) | CLK4ADRB2MEN1KMT2ATP53 | |
| SCHEMBL17055369 | 0.85 | CLK4 (0.54) | CLK4ADRB2MEN1KMT2ATP53 | |
| SCHEMBL18325246 | 0.84 | CLK4 (0.49) | CLK4ADRB2MEN1KMT2ATP53 | |
| SCHEMBL2300946 | 0.84 | MEN1 (0.45) | CLK4ADRB2MEN1KMT2ATP53 | |
| SCHEMBL16625771 | 0.83 | CLK4 (0.61) | CLK4ADRB2MEN1KMT2ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 167 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100534991-C | Heterocyclic inhibitors of ERK 2 and uses thereof | VERTEX PHARMA (US) | 2009-09-02 | — | — | CN | claimed |
| CN-1494541-A | heterocyclic inhibitors of ERK2 and uses thereof | ��̩��˹ҩ��ɷ�����˾ | 2004-05-05 | — | — | CN | claimed |
| US-20240244946-A1 | ORGANIC LIGHT EMITTING DIODE COMPRISING ORGANOMETALLIC COMPOUND AND PLURALITY OF HOST MATERIALS | LG DISPLAY CO., LTD. (KR) | 2024-07-18 | — | — | US | disclosed |
| US-20240244947-A1 | ORGANIC LIGHT EMITTING DIODE COMPRISING ORGANOMETALLIC COMPOUND AND PLURALITY OF HOST MATERIALS | LG DISPLAY CO., LTD. (KR) | 2024-07-18 | — | — | US | disclosed |
| US-20240244947-A1 | ORGANIC LIGHT EMITTING DIODE COMPRISING ORGANOMETALLIC COMPOUND AND PLURALITY OF HOST MATERIALS | LG DISPLAY CO., LTD. (KR) | 2024-07-18 | — | — | US | disclosed |
| US-20240244946-A1 | ORGANIC LIGHT EMITTING DIODE COMPRISING ORGANOMETALLIC COMPOUND AND PLURALITY OF HOST MATERIALS | LG DISPLAY CO., LTD. (KR) | 2024-07-18 | — | — | US | disclosed |
| CN-110088115-B | Organometallic complex, light-emitting element, light-emitting device, electronic device, and lighting device | 株式会社半导体能源研究所 | 2024-05-14 | — | — | CN | disclosed |
| WO-2024086361-A1 | MOLECULAR GLUE DEGRADER COMPOUNDS AND USES THEREOF | NOVARTIS AG (CH) | 2024-04-25 | — | — | WO | disclosed |
| EP-3875151-B1 | ALPHA-METHYL-SUBSTITUTED DIAZABICYCLO [4.3.1] DECANE DERIVATES FOR TREATMENT OF PSYCHIATRIC DISORDERS | UNIV DARMSTADT TECH (DE) | 2023-09-20 | — | — | EP | disclosed |
| US-20230217811-A1 | COMPOUNDS AND ORGANIC ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2023-07-06 | — | — | US | disclosed |
| US-20230217811-A1 | COMPOUNDS AND ORGANIC ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2023-07-06 | — | — | US | disclosed |
| US-4859670-A | 2-Azolylmethyl-2-aryl-1,3-dioxolanes and the salts thereof, agents containing same, and the use thereof | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-08-22 | — | — | US | disclosed |
| EP-0237962-A2 | 2-Azolylmethyl-2-aryl-1,3-dioxolanes and their preparation, compositions containing them and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-09-23 | — | — | EP | disclosed |
| EP-0031796-B1 | 4-HETEROCYCLYL-4'-VINYL-STILBENES | CIBA-GEIGY AG (CH) | 1985-01-23 | — | — | EP | disclosed |
| EP-0020298-B1 | BENZOXAZOLYL STILBENES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS OPTICAL BRIGHTENERS FOR ORGANIC MATERIALS | CIBA-GEIGY AG (CH) | 1983-06-22 | — | — | EP | disclosed |
| US-4366189-A | WHITENERS | CIBA-GEIGY CORPORATION (US) | 1982-12-28 | — | — | US | disclosed |
| US-4297234-A | OPTICAL BRIGHTENERS | CIBA-GEIGY CORPORATION (US) | 1981-10-27 | — | — | US | disclosed |
| EP-0031796-A2 | 4-Heterocyclyl-4'-vinyl-stilbenes | CIBA-GEIGY AG (CH) | 1981-07-08 | — | — | EP | disclosed |
| EP-0020298-A1 | Benzoxazolyl stilbenes, process for their preparation and their use as optical brighteners for organic materials | CIBA-GEIGY AG (CH) | 1980-12-10 | — | — | EP | disclosed |
| US-3940395-A | CNS DEPRESSANT | AMERICAN HOME PRODUCTS CORPORATION (US) | 1976-02-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240244946-A1 | ORGANIC LIGHT EMITTING DIODE COMPRISING ORGANOMETALLIC COMPOUND AND PLURALITY OF HOST MATERIALS | GPX1, PER2, SOD1 | CLK4 556/4885ADRB2 4162/4885MEN1 1557/4885 |
| US-20230217811-A1 | COMPOUNDS AND ORGANIC ELECTRONIC DEVICES | ETV6, CYP2C19, AFF2 | CLK4 3415/4885ADRB2 2062/4885MEN1 292/4885 |
| US-20240244947-A1 | ORGANIC LIGHT EMITTING DIODE COMPRISING ORGANOMETALLIC COMPOUND AND PLURALITY OF HOST MATERIALS | PER2, GPX1, SOD1 | CLK4 567/4885ADRB2 4237/4885MEN1 1517/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.