SCHEMBL25565807

SCHEMBL25565807

CC(CO)(CO)C(=O)OCC(COC(=O)C(CO)CO)(COC(=O)C(C)(CO)CO)COC(=O)C(C)(CO)CO

nearest known ligand 0.36

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
PRKCA P17252 1/20 0.36
ALDH1A1 P00352 1/20 0.32
TP53 P04637 1/20 0.32
CYP3A4 P08684 1/20 0.32
MAPK1 P28482 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
HIF1A Q16665 1/20 0.32
HTT P42858 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25565816 0.92 PRKCA (0.33) PRKCA
SCHEMBL12938546 0.87 MAPK1 (0.39) PRKCAALDH1A1TP53CYP3A4MAPK1
SCHEMBL10030763 0.83 MAPK1 (0.36) PRKCAALDH1A1TP53CYP3A4MAPK1
SCHEMBL11967441 0.81 MAPK1 (0.35) PRKCAALDH1A1TP53CYP3A4MAPK1
SCHEMBL26974017 0.81 MAPK1 (0.35) PRKCAALDH1A1TP53CYP3A4MAPK1
SCHEMBL25566867 0.81
SCHEMBL30634536 0.81 ALDH1A1 (0.42) PRKCAALDH1A1TP53CYP3A4MAPK1
SCHEMBL13714627 0.77 THRB (0.37) PRKCAALDH1A1TP53CYP3A4MAPK1
SCHEMBL9305447 0.77 PRKCA (0.40) PRKCA
SCHEMBL12938597 0.76 PRKCA (0.33) PRKCAALDH1A1TP53CYP3A4MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230149562-A1 CARRIERS FOR EFFICIENT NUCLEIC ACID DELIVERY TIBA BIOTECH LLC (US) 2023-05-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230149562-A1 CARRIERS FOR EFFICIENT NUCLEIC ACID DELIVERY POLN, TLR9, TSG101 PRKCA 1845/4885ALDH1A1 3979/4885TP53 156/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.