SCHEMBL25565980 — predicted protein targets

Predicted protein targets (top 11)

	gene	UniProt	supporting neighbours	confidence
▸	NCF1	P14598	1/20	0.41

▸	GNAO1	P09471	3/20	0.39

▸	GNAI3	P08754	2/20	0.39

▸	GNAI1	P63096	2/20	0.39

▸	DRD2	P14416	2/20	0.38

▸	DRD3	P35462	2/20	0.38

▸	ACHE	P22303	3/20	0.35

▸	HRH3	Q9Y5N1	1/20	0.34

▸	PGR	P06401	1/20	0.32

▸	BCHE	P06276	1/20	0.31

▸	MC4R	P32245	1/20	0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL12440507	0.90	NCF1 (0.45)	NCF1GNAO1GNAI3GNAI1DRD2
SCHEMBL19313003	0.88	GNAO1 (0.39)	NCF1GNAO1GNAI3GNAI1ACHE
SCHEMBL25565975	0.83	NCF1 (0.42)	NCF1GNAO1GNAI3GNAI1DRD2
SCHEMBL27365543	0.80	DRD2 (0.41)	DRD2DRD3ACHEBCHE
SCHEMBL25592936	0.79	NCF1 (0.45)	NCF1GNAO1GNAI3GNAI1ACHE
SCHEMBL22305573	0.78	GNAI3 (0.38)	NCF1GNAO1GNAI3GNAI1DRD2
SCHEMBL22824381	0.78	GNAO1 (0.41)	GNAO1DRD2ACHEHRH3
SCHEMBL25565977	0.78	NCF1 (0.36)	NCF1DRD2DRD3PGRBCHE
SCHEMBL25565978	0.78	NCF1 (0.36)	NCF1DRD2DRD3PGRBCHE
SCHEMBL25565979	0.78	NCF1 (0.36)	NCF1DRD2DRD3PGRBCHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2023083194-A1	WEE1 PROTEIN KINASE DEGRADATION AGENT AND USE THEREOF	杭州格博生物医药有限公司	2023-05-19	—	—	WO	disclosed