Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY1 | P47900 | 9/20 | 0.51 |
| ▸ | HSP90B1 | P14625 | 3/20 | 0.51 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.45 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.42 |
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.42 |
| ▸ | P2RY11 | Q96G91 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.42 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.42 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.42 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.42 |
| ▸ | AHCY | P23526 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25566672 | 0.87 | AHCY (0.56) | HSP90B1ADORA3ADORA1ADORA2ALMNA | |
| SCHEMBL25566632 | 0.86 | ADORA3 (0.53) | P2RY1HSP90B1ADORA3ADORA1ADORA2A | |
| SCHEMBL21257345 | 0.85 | P2RY1 (0.54) | P2RY1ADORA3ADORA1ENPP1P2RY12 | |
| SCHEMBL19464935 | 0.82 | HSP90B1 (0.76) | P2RY1HSP90B1ADORA3ADORA1ADORA2A | |
| SCHEMBL19464932 | 0.82 | HSP90B1 (0.76) | P2RY1HSP90B1ADORA3ADORA1ADORA2A | |
| SCHEMBL26934885 | 0.82 | HSP90B1 (0.76) | P2RY1HSP90B1ADORA3ADORA1ADORA2A | |
| SCHEMBL23098404 | 0.80 | P2RY1 (0.52) | P2RY1HSP90B1ADORA3ADORA1ENPP1 | |
| SCHEMBL22399998 | 0.80 | P2RY1 (0.52) | P2RY1HSP90B1ADORA3ADORA1ENPP1 | |
| SCHEMBL19503291 | 0.80 | P2RY1 (0.52) | P2RY1HSP90B1ADORA3ADORA1ENPP1 | |
| SCHEMBL19807561 | 0.80 | P2RY1 (0.52) | P2RY1HSP90B1ADORA3ADORA1ENPP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023091791-A1 | METHODS OF TREATING NEUROLOGICAL AND CARDIOVASCULAR CONDITIONS | ASTROCYTE PHARMACEUTICALS, INC. (US) | 2023-05-25 | — | — | WO | disclosed |