Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHCY | P23526 | 4/20 | 0.56 |
| ▸ | HSP90B1 | P14625 | 4/20 | 0.53 |
| ▸ | ADORA3 | P0DMS8 | 7/20 | 0.48 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.48 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | NT5E | P21589 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | CHKA | P35790 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25566632 | 0.89 | ADORA3 (0.53) | AHCYHSP90B1ADORA3ADORA1ADORA2A | |
| SCHEMBL25566627 | 0.87 | P2RY1 (0.51) | AHCYHSP90B1ADORA3ADORA1ADORA2A | |
| SCHEMBL22933142 | 0.82 | HSP90B1 (0.79) | HSP90B1ADORA3ADORA1ADORA2A | |
| SCHEMBL19807386 | 0.82 | HSP90B1 (0.79) | HSP90B1ADORA3ADORA1ADORA2A | |
| SCHEMBL19464933 | 0.82 | HSP90B1 (0.79) | HSP90B1ADORA3ADORA1ADORA2A | |
| SCHEMBL21939656 | 0.80 | ADORA3 (0.61) | ADORA3ADORA1ADORA2A | |
| SCHEMBL25565523 | 0.80 | AHCY (0.61) | AHCYHSP90B1ADORA3ADORA1ADORA2A | |
| SCHEMBL19503864 | 0.78 | ADORA3 (0.69) | HSP90B1ADORA3ADORA1ADORA2A | |
| SCHEMBL17243941 | 0.78 | ADORA3 (0.60) | HSP90B1ADORA3ADORA1ADORA2A | |
| SCHEMBL25566681 | 0.75 | ADORA3 (0.71) | ADORA3ADORA1ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023091791-A1 | METHODS OF TREATING NEUROLOGICAL AND CARDIOVASCULAR CONDITIONS | ASTROCYTE PHARMACEUTICALS, INC. (US) | 2023-05-25 | — | — | WO | disclosed |