Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 18/20 | 0.62 |
| ▸ | ADORA1 | P30542 | 7/20 | 0.62 |
| ▸ | ADORA2B | P29275 | 4/20 | 0.52 |
| ▸ | TMIGD3 | P0DMS9 | 1/20 | 0.44 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25566698 | 0.89 | ADORA3 (0.57) | ADORA3ADORA1ADORA2BTMIGD3ADORA2A | |
| SCHEMBL3727163 | 0.77 | ADORA3 (1.00) | ADORA3ADORA1TMIGD3HSP90B1 | |
| SCHEMBL25566692 | 0.76 | ADORA3 (0.68) | ADORA3ADORA1ADORA2BTMIGD3ADORA2A | |
| SCHEMBL25566746 | 0.75 | ADORA3 (0.68) | ADORA3ADORA1ADORA2BTMIGD3ADORA2A | |
| SCHEMBL19503864 | 0.73 | ADORA3 (0.69) | ADORA3ADORA1TMIGD3HSP90B1ADORA2A | |
| SCHEMBL22359924 | 0.71 | ADORA3 (0.71) | ADORA3ADORA1TMIGD3 | |
| SCHEMBL25565810 | 0.70 | ADORA3 (0.62) | ADORA3ADORA1TMIGD3HSP90B1ADORA2A | |
| SCHEMBL10677210 | 0.70 | AHCY (0.73) | ADORA3ADORA1ADORA2B | |
| SCHEMBL10677199 | 0.70 | AHCY (0.73) | ADORA3ADORA1ADORA2B | |
| SCHEMBL21939669 | 0.69 | ADORA3 (0.71) | ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023091791-A1 | METHODS OF TREATING NEUROLOGICAL AND CARDIOVASCULAR CONDITIONS | ASTROCYTE PHARMACEUTICALS, INC. (US) | 2023-05-25 | — | — | WO | disclosed |