Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 7/20 | 0.47 |
| ▸ | HTR2C | P28335 | 6/20 | 0.47 |
| ▸ | HTR2B | P41595 | 6/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 10/20 | 0.47 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.44 |
| ▸ | TMIGD3 | P0DMS9 | 2/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | TSPO | P30536 | 1/20 | 0.40 |
| ▸ | NT5E | P21589 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.39 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.39 |
| ▸ | IARS1 | P41252 | 1/20 | 0.39 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25566632 | 0.73 | ADORA3 (0.53) | ADORA1ADORA3P2RY1TMIGD3ADORA2A | |
| SCHEMBL21257345 | 0.72 | P2RY1 (0.54) | ADORA1ADORA3P2RY1 | |
| SCHEMBL19459478 | 0.70 | HTR2C (0.66) | ADORA1HTR2CHTR2BADORA3TMIGD3 | |
| SCHEMBL25566746 | 0.69 | ADORA3 (0.68) | ADORA1ADORA3TMIGD3ADORA2ATMEM97 | |
| SCHEMBL25566680 | 0.69 | ADORA3 (0.62) | ADORA1ADORA3TMIGD3ADORA2AHSP90B1 | |
| SCHEMBL2407503 | 0.68 | ADORA3 (0.59) | ADORA1ADORA3P2RY1TMIGD3ADORA2A | |
| SCHEMBL21710880 | 0.67 | ADORA3 (0.65) | ADORA1HTR2CHTR2BADORA3P2RY1 | |
| SCHEMBL25566756 | 0.67 | ADORA3 (0.65) | ADORA1HTR2CHTR2BADORA3P2RY1 | |
| SCHEMBL10121327 | 0.67 | ADORA3 (0.67) | ADORA1HTR2CHTR2BADORA3P2RY1 | |
| SCHEMBL27387953 | 0.66 | P2RY1 (0.49) | ADORA3P2RY1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023091791-A1 | METHODS OF TREATING NEUROLOGICAL AND CARDIOVASCULAR CONDITIONS | ASTROCYTE PHARMACEUTICALS, INC. (US) | 2023-05-25 | — | — | WO | disclosed |