Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.49 |
| ▸ | LTA4H | P09960 | 1/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | GBA1 | P04062 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.41 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.41 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.41 |
| ▸ | NCF1 | P14598 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17108495 | 0.86 | LMNA (0.59) | LMNAALDH1A1CXCR3LTA4HHRH3 | |
| SCHEMBL16215680 | 0.83 | ALDH1A1 (0.61) | LMNAALDH1A1LTA4HHRH3POLB | |
| SCHEMBL20804051 | 0.82 | ALDH1A1 (0.54) | LMNAALDH1A1LTA4HHRH3CYP3A4 | |
| SCHEMBL10690328 | 0.82 | LMNA (0.80) | LMNAALDH1A1HRH3POLBSIGMAR1 | |
| SCHEMBL1427542 | 0.81 | ALDH1A1 (0.58) | LMNAALDH1A1LTA4HHRH3CYP3A4 | |
| SCHEMBL4259787 | 0.81 | ALDH1A1 (0.61) | LMNAALDH1A1CXCR3HRH3CYP3A4 | |
| SCHEMBL12013906 | 0.81 | SIGMAR1 (0.65) | LMNAALDH1A1LTA4HCYP3A4HSD17B10 | |
| SCHEMBL6205194 | 0.80 | ALDH1A1 (0.59) | LMNAALDH1A1CXCR3HRH3HRH4 | |
| Ammonia Solution, Strong SCHEMBL14735243 | 0.79 | SIGMAR1 (0.63) | LMNAALDH1A1LTA4HCYP3A4HSD17B10 | |
| SCHEMBL3153045 | 0.78 | ALDH1A1 (0.88) | LMNAALDH1A1HRH3POLBHRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023078207-A1 | 6-POSITION-SUBSTITUTED INDOLINONE DERIVATIVE, PREPARATION METHOD THEREFOR, AND MEDICAL USE THEREOF | 南京中医药大学 | 2023-05-11 | — | — | WO | disclosed |