SCHEMBL25567809

SCHEMBL25567809

O=C(Oc1ccccc1)c1ccc2c(c1)CCO2

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRM5 P41594 1/20 0.52
PRKCI P41743 1/20 0.51
CTNNB1 P35222 1/20 0.51
WNT3A P56704 1/20 0.51
NPC1 O15118 2/20 0.51
RAB9A P51151 2/20 0.51
MAPT P10636 4/20 0.47
ALDH1A1 P00352 2/20 0.47
MAPK1 P28482 1/20 0.46
KMT2A Q03164 2/20 0.46
MEN1 O00255 1/20 0.46
PARP10 Q53GL7 1/20 0.45
NSD2 O96028 1/20 0.45
TAS1R3 Q7RTX0 2/20 0.45
TAS1R1 Q7RTX1 2/20 0.45
MAOA P21397 1/20 0.45
MAOB P27338 1/20 0.45
HDAC3 O15379 1/20 0.45
HDAC4 P56524 1/20 0.45
HDAC1 Q13547 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15715954 0.86 MAPT (0.50) GRM5PRKCINPC1RAB9AMAPT
SCHEMBL7439487 0.80 KMT2A (0.53) PRKCICTNNB1WNT3ANPC1RAB9A
SCHEMBL4517760 0.79 CTNNB1 (0.59) PRKCICTNNB1WNT3ANPC1RAB9A
SCHEMBL7808230 0.79 NPC1 (0.65) PRKCICTNNB1WNT3ANPC1RAB9A
SCHEMBL3490016 0.79 PRKCI (0.57) PRKCINPC1RAB9AALDH1A1MAPK1
SCHEMBL31417661 0.79 PRKCI (0.57) PRKCINPC1RAB9AALDH1A1MAPK1
SCHEMBL1395976 0.78 PRKCI (0.64) PRKCICTNNB1WNT3ANPC1RAB9A
SCHEMBL11695864 0.78 ALDH1A1 (0.60) CTNNB1WNT3ANPC1RAB9AMAPT
SCHEMBL11695870 0.77 MAPT (0.47) MAPTALDH1A1MAPK1KMT2AMEN1
SCHEMBL29177443 0.77 ALDH1A1 (0.66) NPC1RAB9AMAPTALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230167447-A1 Compositions for FNIP1/FNIP2 Gene Modulation and Methods Thereof GENETIC INTELLIGENCE INC (US) 2023-06-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230167447-A1 Compositions for FNIP1/FNIP2 Gene Modulation and Methods Thereof FNIP1, FN1, TNNC1 GRM5 4047/4885PRKCI 1412/4885CTNNB1 3955/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.