SCHEMBL25567841

SCHEMBL25567841

O=C(c1ccccc1O)C1C=Cc2ccccc21

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PIN1 Q13526 1/20 0.45
HPGD P15428 7/20 0.41
KDM4E B2RXH2 6/20 0.41
ALDH1A1 P00352 4/20 0.41
SMN1; SMN2 Q16637 3/20 0.41
CA12 O43570 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
HMGB1 P09429 1/20 0.41
CA4 P22748 1/20 0.41
CA6 P23280 1/20 0.41
CA7 P43166 1/20 0.41
CA9 Q16790 1/20 0.41
NAPRT Q6XQN6 1/20 0.41
CA14 Q9ULX7 1/20 0.41
HSD17B10 Q99714 4/20 0.40
TSHR P16473 2/20 0.40
MAPT P10636 1/20 0.40
LIG1 P18858 1/20 0.40
GAA P10253 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28516568 0.79 ATM (0.36) ALDH1A1SMN1; SMN2HSD17B10TSHRMAPT
SCHEMBL25567842 0.77 ATM (0.42) ALDH1A1SMN1; SMN2NAPRTTSHRMAPT
SCHEMBL29282859 0.77 CES2 (0.40) HPGDCA12CA1CA2CA4
SCHEMBL31068436 0.76 HTR6 (0.41) HPGDKDM4EALDH1A1SMN1; SMN2HSD17B10
SCHEMBL9309445 0.76 HTR2A (0.38) HPGDKDM4EALDH1A1SMN1; SMN2HSD17B10
SCHEMBL29401941 0.74 EDNRA (0.39) ALDH1A1SMN1; SMN2TSHRMEN1KMT2A
SCHEMBL31147849 0.74 HTR6 (0.40) KDM4EALDH1A1SMN1; SMN2TSHRLMNA
SCHEMBL63928 0.74 EDNRA (0.39) ALDH1A1SMN1; SMN2TSHRMEN1KMT2A
SCHEMBL3609519 0.74 HTR2A (0.36) KDM4EALDH1A1SMN1; SMN2TSHRLMNA
SCHEMBL3246033 0.73 HTR2A (0.35) KDM4EALDH1A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230167447-A1 Compositions for FNIP1/FNIP2 Gene Modulation and Methods Thereof GENETIC INTELLIGENCE INC (US) 2023-06-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230167447-A1 Compositions for FNIP1/FNIP2 Gene Modulation and Methods Thereof FNIP1, FN1, TNNC1 PIN1 1805/4885HPGD 3545/4885KDM4E 4333/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.